{"id":11294,"date":"2024-01-22T03:27:44","date_gmt":"2024-01-22T03:27:44","guid":{"rendered":"https:\/\/gd-1.com\/?p=11294"},"modified":"2024-03-20T07:20:15","modified_gmt":"2024-03-20T07:20:15","slug":"vai-tro-cua-phan-lap-va-nhan-dien-vi-sinh-vat-noi-sinh-trong-kiem-soat-chat-luong-duoc-pham","status":"publish","type":"post","link":"https:\/\/gd-1.com\/vai-tro-cua-phan-lap-va-nhan-dien-vi-sinh-vat-noi-sinh-trong-kiem-soat-chat-luong-duoc-pham\/","title":{"rendered":"Vai tr\u00f2 c\u1ee7a ph\u00e2n l\u1eadp v\u00e0 nh\u1eadn di\u1ec7n vi sinh v\u1eadt n\u1ed9i sinh trong ki\u1ec3m so\u00e1t ch\u1ea5t l\u01b0\u1ee3ng d\u01b0\u1ee3c ph\u1ea9m"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_69_1 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<label class=\"ez-toc-title ez-toc-toggle\" style=\"cursor:pointer\">T\u00f3m t\u1eaft n\u1ed9i dung<\/label>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #0a0a0a;color:#0a0a0a\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #0a0a0a;color:#0a0a0a\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/gd-1.com\/vai-tro-cua-phan-lap-va-nhan-dien-vi-sinh-vat-noi-sinh-trong-kiem-soat-chat-luong-duoc-pham\/#Thuc_hien_phan_lap_vi_sinh_vat_noi_sinh\" title=\"Th\u1ef1c hi\u1ec7n ph\u00e2n l\u1eadp vi sinh v\u1eadt n\u1ed9i sinh\">Th\u1ef1c hi\u1ec7n ph\u00e2n l\u1eadp vi sinh v\u1eadt n\u1ed9i sinh<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/gd-1.com\/vai-tro-cua-phan-lap-va-nhan-dien-vi-sinh-vat-noi-sinh-trong-kiem-soat-chat-luong-duoc-pham\/#Ket_luan\" title=\"K\u1ebft lu\u1eadn\">K\u1ebft lu\u1eadn<\/a><\/li><\/ul><\/nav><\/div>\n<p>\u00d4 nhi\u1ec5m VI SINH V\u1eacT trong d\u01b0\u1ee3c ph\u1ea9m \u1ea3nh h\u01b0\u1edfng x\u1ea5u \u0111\u1ebfn hi\u1ec7u qu\u1ea3 v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng c\u1ee7a ch\u00fang, g\u00e2y ra r\u1ee7i ro \u0111\u00e1ng k\u1ec3 cho b\u1ec7nh nh\u00e2n. Chu\u1ea9n b\u1ecb v\u00e0 b\u1ea3o tr\u00ec li\u00ean t\u1ee5c \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o hi\u1ec7u l\u1ef1c v\u00e0 \u0111\u1ed9 an to\u00e0n c\u1ee7a thu\u1ed1c v\u00f4 tr\u00f9ng, b\u1eaft bu\u1ed9c ph\u1ea3i gi\u00e1m s\u00e1t ch\u1ea5t l\u01b0\u1ee3ng c\u1ee7a m\u00f4i tr\u01b0\u1eddng ch\u1ebf bi\u1ebfn v\u00f4 tr\u00f9ng b\u1eb1ng c\u00e1ch tri\u1ec3n khai ch\u01b0\u01a1ng tr\u00ecnh gi\u00e1m s\u00e1t m\u00f4i tr\u01b0\u1eddng (EM) hi\u1ec7u qu\u1ea3 v\u00e0 m\u1ea1nh m\u1ebd. \u0110i\u1ec1u n\u00e0y li\u00ean quan \u0111\u1ebfn vi\u1ec7c \u0111\u00e1nh gi\u00e1 c\u00e1c ngu\u1ed3n \u00f4 nhi\u1ec5m ch\u00ednh trong qu\u00e1 tr\u00ecnh v\u00f4 tr\u00f9ng nh\u01b0 nh\u00e2n s\u1ef1, c\u01a1 s\u1edf v\u1eadt ch\u1ea5t, ti\u1ec7n \u00edch, v\u1eadt li\u1ec7u, thi\u1ebft b\u1ecb v\u00e0 quy tr\u00ecnh s\u1ea3n xu\u1ea5t. Vi\u1ec7c theo d\u00f5i v\u00e0 c\u1eadp nh\u1eadt li\u00ean t\u1ee5c d\u1eef li\u1ec7u EM kh\u00f4ng ch\u1ec9 gi\u00fap x\u00e1c \u0111\u1ecbnh t\u00ednh hi\u1ec7u qu\u1ea3 c\u1ee7a quy tr\u00ecnh l\u00e0m s\u1ea1ch v\u00e0 kh\u1eed tr\u00f9ng m\u00e0 c\u00f2n cho ph\u00e9p theo d\u00f5i ch\u1eb7t ch\u1ebd nh\u1eefng thay \u0111\u1ed5i trong h\u1ec7 vi sinh v\u1eadt c\u1ee5c b\u1ed9, x\u00e1c \u0111\u1ecbnh b\u1ea5t k\u1ef3 d\u1ea5u hi\u1ec7u c\u1ea3nh b\u00e1o s\u1edbm khi c\u00e1c bi\u1ec7n ph\u00e1p ki\u1ec3m so\u00e1t kh\u00f4ng th\u00e0nh c\u00f4ng.<\/p>\n<p>Ph\u00e2n l\u1eadp n\u1ed9i sinh l\u00e0 nu\u00f4i c\u1ea5y vi sinh v\u1eadt \u0111\u01b0\u1ee3c thu h\u1ed3i t\u1eeb m\u00f4i tr\u01b0\u1eddng s\u1ea3n xu\u1ea5t, bao g\u1ed3m ph\u00f2ng s\u1ea1ch, h\u1ec7 th\u1ed1ng n\u01b0\u1edbc, nguy\u00ean li\u1ec7u th\u00f4, s\u1ef1 c\u1ed1 \u00f4 nhi\u1ec5m v\u00e0 thi\u1ebft b\u1ecb. C\u00e1c ch\u1ee7ng n\u00e0y l\u00e0 \u0111\u1ea1i di\u1ec7n c\u1ee7a h\u1ec7 vi sinh v\u1eadt \u0111\u1ecba ph\u01b0\u01a1ng v\u00e0 c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi b\u1eb1ng c\u00e1c t\u00ean kh\u00e1c nh\u01b0 ph\u00e2n l\u1eadp m\u00f4i tr\u01b0\u1eddng, ph\u00e2n l\u1eadp th\u1ef1c v\u1eadt, ph\u00e2n l\u1eadp ki\u1ec3u t\u1ef1 nhi\u00ean, ph\u00e2n l\u1eadp nh\u00e0 m\u00e1y ho\u1eb7c ph\u00e2n l\u1eadp c\u01a1 s\u1edf.<\/p>\n<p>Nh\u1eefng c\u1ea3nh b\u00e1o v\u1ec1 v\u1ea5n \u0111\u1ec1 n\u00e0y \u0111\u00e3 gi\u1ea3m d\u1ea7n trong nh\u1eefng n\u0103m g\u1ea7n \u0111\u00e2y, \u0111i\u1ec1u n\u00e0y c\u00f3 l\u1ebd cho th\u1ea5y r\u1eb1ng h\u1ea7u h\u1ebft c\u00e1c doanh nghi\u1ec7p \u0111\u00e3 ch\u1ea5p nh\u1eadn \u0111\u00e2y l\u00e0 m\u1ed9t y\u00eau c\u1ea7u ph\u00e1p l\u00fd v\u00e0 do \u0111\u00f3 \u0111\u00e3 m\u1edf r\u1ed9ng danh s\u00e1ch c\u00e1c ch\u1ee7ng th\u1eed nghi\u1ec7m b\u1ed5 sung c\u1ee7a h\u1ecd \u0111\u1ec3 \u0111\u01b0a c\u00e1c ch\u1ee7ng ph\u00e2n l\u1eadp n\u1ed9i b\u1ed9 v\u00e0o th\u1eed th\u00e1ch th\u00fac \u0111\u1ea9y t\u0103ng tr\u01b0\u1edfng c\u1ee7a m\u00f4i tr\u01b0\u1eddng nu\u00f4i c\u1ea5y, nghi\u00ean c\u1ee9u hi\u1ec7u qu\u1ea3 kh\u1eed tr\u00f9ng, nh\u1eadn di\u1ec7n x\u00e9t nghi\u1ec7m vi sinh v\u1eadt v\u00e0 th\u1eed nghi\u1ec7m hi\u1ec7u qu\u1ea3 kh\u00e1ng khu\u1ea9n.<\/p>\n<p>V\u00ec ph\u00e2n l\u1eadp n\u1ed9i sinh \u0111\u01b0\u1ee3c xem l\u00e0 \u0111\u1ea1i di\u1ec7n c\u1ee7a h\u1ec7 vi sinh v\u1eadt trong c\u01a1 s\u1edf v\u00e0 ch\u01b0a \u0111\u01b0\u1ee3c c\u1ea5y truy\u1ec1n nhi\u1ec1u l\u1ea7n, c\u00f3 th\u1ec3 l\u1eadp lu\u1eadn r\u1eb1ng ch\u00fang l\u00e0 l\u1ef1a ch\u1ecdn t\u1ed1t \u0111\u1ec3 mang l\u1ea1i s\u1ef1 tin c\u1eady cao h\u01a1n trong vi\u1ec7c ki\u1ec3m so\u00e1t ch\u1ea5t l\u01b0\u1ee3ng vi sinh. H\u01a1n n\u1eefa, h\u1ec7 vi sinh v\u1eadt trong h\u1ec7 th\u1ed1ng n\u01b0\u1edbc v\u00e0 ph\u00f2ng s\u1ea1ch th\u00edch nghi v\u1edbi c\u00e1c t\u00e1c nh\u00e2n g\u00e2y \u00e1p l\u1ef1c m\u00f4i tr\u01b0\u1eddng (nh\u01b0 thi\u1ebfu ch\u1ea5t dinh d\u01b0\u1ee1ng, ch\u1ea5t kh\u1eed tr\u00f9ng, \u00e1p l\u1ef1c th\u1ea9m th\u1ea5u, tia UV) d\u1eabn \u0111\u1ebfn s\u1ef1 bi\u1ebfn \u0111\u1ed5i ki\u1ec3u h\u00ecnh trong c\u00f9ng m\u1ed9t lo\u00e0i v\u00e0 do \u0111\u00f3 ho\u1ea1t \u0111\u1ed9ng kh\u00e1c nhau. Do \u0111\u00f3, c\u00e1c vi sinh v\u1eadt b\u1ea3n \u0111\u1ecba ch\u1ecbu \u00e1p l\u1ef1c v\u00e0 th\u00edch nghi c\u00f3 th\u1ec3 b\u1ed5 sung t\u1ed1t cho s\u1ed1 l\u01b0\u1ee3ng nh\u1ecf c\u00e1c ch\u1ee7ng th\u1eed nghi\u1ec7m ti\u00eau chu\u1ea9n cho th\u1eed th\u00e1ch th\u1eed nghi\u1ec7m m\u00f4i tr\u01b0\u1eddng nu\u00f4i c\u1ea5y v\u00e0 c\u00e1c nghi\u00ean c\u1ee9u nh\u1eadn di\u1ec7n kh\u00e1c, c\u0169ng nh\u01b0 n\u00e2ng cao \u0111\u1ed9 tin c\u1eady c\u1ee7a c\u00e1c ph\u01b0\u01a1ng ph\u00e1p th\u1eed nghi\u1ec7m. Tuy nhi\u00ean, c\u00e1c ch\u1ee7ng ph\u00e2n l\u1eadp n\u1ed9i b\u1ed9 r\u1ea5t kh\u00f3 ti\u00eau chu\u1ea9n h\u00f3a, khi\u1ebfn vi\u1ec7c so s\u00e1nh c\u00e1c ph\u01b0\u01a1ng ph\u00e1p th\u1eed nghi\u1ec7m gi\u1eefa c\u00e1c ph\u00f2ng th\u00ed nghi\u1ec7m kh\u00e1c nhau tr\u1edf n\u00ean kh\u00f3 kh\u0103n. Ngo\u00e0i ra, t\u00ednh \u1ed5n \u0111\u1ecbnh c\u1ee7a c\u00e1c thu\u1ed9c t\u00ednh \u201ct\u1ef1 nhi\u00ean\u201d c\u1ee7a ch\u00fang khi nu\u00f4i c\u1ea5y trong m\u00f4i tr\u01b0\u1eddng ph\u00f2ng th\u00ed nghi\u1ec7m th\u01b0\u1eddng b\u1ecb h\u1ea1n ch\u1ebf. Nu\u00f4i c\u1ea5y c\u1ea5p hai li\u00ean t\u1ee5c tr\u00ean m\u00f4i tr\u01b0\u1eddng gi\u00e0u dinh d\u01b0\u1ee1ng g\u1ea7n nh\u01b0 th\u00fac \u0111\u1ea9y s\u1ef1 ti\u1ebfn h\u00f3a c\u1ee7a ch\u1ee7ng g\u00e2y m\u1ea5t ph\u1ea3n \u1ee9ng th\u00edch nghi \u00e1p l\u1ef1c; tuy nhi\u00ean, nh\u1eefng ki\u1ec3u h\u00ecnh \u0111\u1ed9c \u0111\u00e1o n\u00e0y b\u1ecb m\u1ea5t \u0111i nhanh ch\u00f3ng. M\u1ed9t trong nh\u1eefng l\u1eadp lu\u1eadn ph\u1ed5 bi\u1ebfn \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 m\u1ea5t \u0111i c\u00e1c \u0111\u1eb7c t\u00ednh c\u1ee7a lo\u00e0i t\u1ef1 nhi\u00ean l\u00e0 b\u1eb1ng c\u00e1ch gi\u1ea3m thi\u1ec3u s\u1ed1 l\u01b0\u1ee3ng nu\u00f4i c\u1ea5y c\u1ea5p hai c\u1ee7a c\u00e1c ch\u1ee7ng ph\u00e2n l\u1eadp n\u1ed9i sinh.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Thuc_hien_phan_lap_vi_sinh_vat_noi_sinh\"><\/span><strong>Th\u1ef1c hi\u1ec7n ph\u00e2n l\u1eadp vi sinh v\u1eadt n\u1ed9i sinh<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u0110i\u1ec1u quan tr\u1ecdng l\u00e0 ph\u1ea3i l\u1ef1a ch\u1ecdn ch\u00ednh th\u1ee9c c\u00e1ch ti\u1ebfp c\u1eadn c\u00e1c ch\u1ee7ng n\u1ed9i sinh trong m\u1ed9t quy tr\u00ecnh, v\u00ec vi\u1ec7c kh\u00f4ng l\u00e0m nh\u01b0 v\u1eady s\u1ebd g\u00e2y ra r\u1ee7i ro tu\u00e2n th\u1ee7. M\u1eb7c d\u00f9 c\u00e1c b\u1ea3n t\u00f3m t\u1eaft v\u00e0 c\u00e1c v\u0103n b\u1ea3n h\u01b0\u1edbng d\u1eabn quy \u0111\u1ecbnh \u0111\u00e3 \u0111\u01b0a ra c\u00e1c khuy\u1ebfn ngh\u1ecb v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng c\u00e1c thi\u1ebft b\u1ecb ph\u00e2n l\u1eadp n\u1ed9i sinh, h\u1ecd h\u1ea7u nh\u01b0 thi\u1ebfu h\u01b0\u1edbng d\u1eabn c\u1ee5 th\u1ec3 v\u1ec1 c\u00e1ch l\u1ef1a ch\u1ecdn. Tuy nhi\u00ean, m\u1ed9t c\u00e1ch ti\u1ebfp c\u1eadn ph\u1ed5 bi\u1ebfn l\u00e0 hi\u1ec3u m\u1ee5c \u0111\u00edch s\u1eed d\u1ee5ng c\u1ee7a m\u00f4i tr\u01b0\u1eddng nu\u00f4i c\u1ea5y tr\u01b0\u1edbc khi x\u00e1c \u0111\u1ecbnh c\u00e1c ph\u00e2n l\u1eadp vi sinh v\u1eadt b\u1ea3n \u0111\u1ecba c\u00f3 li\u00ean quan \u0111\u1ec3 \u0111\u01b0a v\u00e0o. V\u00ed d\u1ee5: \u0111\u01b0a c\u00e1c ch\u1ee7ng ph\u00e2n l\u1eadp \u0111\u01b0\u1ee3c li\u00ean k\u1ebft v\u1edbi EM v\u00e0 c\u00e1c h\u1ec7 th\u1ed1ng ti\u1ec7n \u00edch v\u00e0o th\u00e1ch th\u1ee9c GPT c\u1ee7a m\u00f4i tr\u01b0\u1eddng nu\u00f4i c\u1ea5y EM. T\u01b0\u01a1ng t\u1ef1 nh\u01b0 v\u1eady, c\u1ea7n xem x\u00e9t vi\u1ec7c \u0111\u01b0a c\u00e1c ch\u1ee7ng ph\u00e2n l\u1eadp t\u1eeb th\u1eed nghi\u1ec7m \u0111\u1ed9 v\u00f4 tr\u00f9ng v\u00e0 l\u1ed7i n\u1ea1p m\u00f4i tr\u01b0\u1eddng v\u00e0o GPT c\u1ee7a m\u00f4i tr\u01b0\u1eddng th\u1eed nghi\u1ec7m \u0111\u1ed9 v\u00f4 tr\u00f9ng v\u00e0 m\u00f4i tr\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 m\u00f4 ph\u1ecfng quy tr\u00ecnh v\u00f4 tr\u00f9ng.<\/p>\n<figure id=\"attachment_11295\" aria-describedby=\"caption-attachment-11295\" style=\"width: 767px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-11295\" src=\"https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.09.png\" alt=\"\" width=\"767\" height=\"356\" srcset=\"https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.09.png 1260w, https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.09-300x139.png 300w, https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.09-1024x475.png 1024w, https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.09-768x356.png 768w, https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.09-510x236.png 510w\" sizes=\"(max-width: 767px) 100vw, 767px\" \/><figcaption id=\"caption-attachment-11295\" class=\"wp-caption-text\">H\u00ecnh 1: K\u1ebft qu\u1ea3 ki\u1ec3m so\u00e1t ch\u1ea5t l\u01b0\u1ee3ng c\u1ee7a c\u00e1c l\u00f4 BIOBALL\u00ae 550 \u0111\u01b0\u1ee3c ph\u00e1t h\u00e0nh trong 5 n\u0103m (2019 \u0111\u1ebfn 2023), \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t t\u1eeb c\u00e1c ch\u1ee7ng ph\u00e2n l\u1eadp Micrococcus luteus nh\u1eadn \u0111\u01b0\u1ee3c t\u1eeb c\u00e1c khu v\u1ef1c kh\u00e1c nhau. Thanh l\u1ed7i bi\u1ec3u th\u1ecb \u0111\u1ed9 l\u1ec7ch chu\u1ea9n d\u1ef1a tr\u00ean c\u00e1c ph\u1ea7n l\u1eb7p l\u1ea1i.<\/figcaption><\/figure>\n<figure id=\"attachment_11296\" aria-describedby=\"caption-attachment-11296\" style=\"width: 504px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-11296\" src=\"https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.16-300x232.png\" alt=\"\" width=\"504\" height=\"390\" srcset=\"https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.16-300x232.png 300w, https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.16-1024x791.png 1024w, https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.16-768x593.png 768w, https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.16-510x394.png 510w, https:\/\/gd-1.com\/wp-content\/uploads\/2024\/01\/Anh-man-hinh-2024-01-22-luc-10.08.16.png 1168w\" sizes=\"(max-width: 504px) 100vw, 504px\" \/><figcaption id=\"caption-attachment-11296\" class=\"wp-caption-text\">H\u00ecnh 2: Ph\u00e2n ph\u1ed1i c\u00e1c ch\u1ee7ng ph\u00e2n l\u1eadp n\u1ed9i b\u1ed9 \u0111\u01b0\u1ee3c chuy\u1ec3n \u0111\u1ed5i sang \u0111\u1ecbnh d\u1ea1ng BIOBALL\u00ae nh\u01b0 m\u1ed9t ph\u1ea7n c\u1ee7a BIOBALL\u00ae c\u1ee7a bioM\u00e9rieux D\u1ecbch v\u1ee5 t\u00f9y ch\u1ec9nh (2019-2023). GPC: c\u1ea7u khu\u1ea9n gram d\u01b0\u01a1ng; GPR: Que gram d\u01b0\u01a1ng; GNR: Thanh gram \u00e2m.<\/figcaption><\/figure>\n<p>Vi\u1ec7c chu\u1ea9n b\u1ecb v\u00e0 duy tr\u00ec li\u00ean t\u1ee5c c\u00e1c ch\u1ee7ng vi sinh v\u1eadt ph\u00e2n l\u1eadp l\u00e0 m\u1ed9t th\u00e1ch th\u1ee9c, g\u00e2y th\u00eam \u00e1p l\u1ef1c l\u00ean ngu\u1ed3n l\u1ef1c c\u1ee7a ph\u00f2ng th\u00ed nghi\u1ec7m<br \/>\nv\u00e0 t\u0103ng chi ph\u00ed ho\u1ea1t \u0111\u1ed9ng t\u1ed5ng th\u1ec3. Ngo\u00e0i ra, vi\u1ec7c chu\u1ea9n b\u1ecb huy\u1ec1n ph\u00f9 vi sinh v\u1eadt n\u1ed9i sinh c\u00f3 nguy c\u01a1 bi\u1ebfn \u0111\u1ed5i ch\u1ea5t c\u1ea5y cao. Do \u0111\u00f3, c\u00e1c chuy\u00ean gia khuy\u1ebfn ngh\u1ecb n\u00ean th\u1ef1c hi\u1ec7n c\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh c\u1ee7a huy\u1ec1n ph\u00f9 vi sinh v\u1eadt trong qu\u00e1 tr\u00ecnh b\u1ea3o qu\u1ea3n v\u00e0 \u1ea5n \u0111\u1ecbnh ng\u00e0y h\u1ebft h\u1ea1n cho huy\u1ec1n ph\u00f9 ti\u00eau chu\u1ea9n, \u0111i\u1ec1u n\u00e0y c\u00e0ng l\u00e0m t\u0103ng th\u00eam \u0111\u1ed9 ph\u1ee9c t\u1ea1p v\u00e0 chi ph\u00ed c\u1ee7a quy tr\u00ecnh.<\/p>\n<p><a href=\"https:\/\/gd-1.com\/san-pham\/chung-vi-sinh-dinh-luong-bioball\/\">BIOBALL\u00ae<\/a> gi\u00fap \u0111\u01a1n gi\u1ea3n h\u00f3a vi\u1ec7c tri\u1ec3n khai c\u00e1c ch\u1ee7ng vi sinh n\u1ed9i sinh v\u00e0 mang l\u1ea1i s\u1ef1 t\u1ef1 tin cao h\u01a1n trong vi\u1ec7c ki\u1ec3m so\u00e1t ch\u1ea5t l\u01b0\u1ee3ng vi sinh th\u01b0\u1eddng quy b\u1eb1ng c\u00e1ch b\u1ea3o qu\u1ea3n v\u00e0 s\u1ea3n xu\u1ea5t c\u00e1c ch\u1ee7ng ph\u00e2n l\u1eadp n\u1ed9i b\u1ed9, thu \u0111\u01b0\u1ee3c \u1edf d\u1ea1ng <a href=\"https:\/\/gd-1.com\/san-pham\/chung-vi-sinh-dinh-luong-bioball\/\">BIOBALL\u00ae<\/a> s\u1eb5n s\u00e0ng s\u1eed d\u1ee5ng. N\u00f3 s\u1eed d\u1ee5ng c\u00f4ng ngh\u1ec7 \u0111o t\u1ebf b\u00e0o \u0111\u1ed9c quy\u1ec1n \u0111\u1ec3 t\u1ea1o ra v\u1eadt li\u1ec7u tham chi\u1ebfu \u0111\u1ecbnh l\u01b0\u1ee3ng ch\u00ednh x\u00e1c, th\u1ec3 hi\u1ec7n s\u1ed1 l\u01b0\u1ee3ng CFU nh\u1ea5t qu\u00e1n theo t\u1eebng \u0111\u1ee3t (H\u00ecnh 1). H\u00e0ng n\u0103m, BIOBALL\u00ae ho\u1ea1t \u0111\u1ed9ng v\u1edbi s\u1ed1 l\u01b0\u1ee3ng l\u1edbn ph\u00e2n l\u1eadp n\u1ed9i sinh t\u00f9y c\u00e1c n\u01a1i kh\u00e1c nhau, ph\u00e1t tri\u1ec3n th\u00e0nh <a href=\"https:\/\/gd-1.com\/san-pham\/chung-vi-sinh-dinh-luong-bioball\/\">BIOBALL\u00ae<\/a> ch\u00ednh x\u00e1c \u0111\u00e1p \u1ee9ng nhu c\u1ea7u ki\u1ec3m tra QC c\u1ee5 th\u1ec3 c\u1ee7a c\u00e1c nh\u00e0 s\u1ea3n xu\u1ea5t d\u01b0\u1ee3c ph\u1ea9m.<\/p>\n<p>C\u00e1c vi sinh v\u1eadt ph\u1ed5 bi\u1ebfn \u0111\u01b0\u1ee3c ph\u00e2n l\u1eadp trong ph\u00f2ng th\u00ed nghi\u1ec7m d\u01b0\u1ee3c ph\u1ea9m<\/p>\n<p>Trong th\u1eadp k\u1ef7 qua, c\u00e1c ch\u1ee7ng ph\u00e2n l\u1eadp n\u1ed9i b\u1ed9 \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n th\u00e0nh <a href=\"https:\/\/gd-1.com\/san-pham\/chung-vi-sinh-dinh-luong-bioball\/\">BIOBALL\u00ae<\/a> v\u1eabn c\u00f3 t\u00ednh nh\u1ea5t qu\u00e1n cao. Sau \u0111\u00e2y l\u00e0 danh s\u00e1ch m\u1ed9t s\u1ed1 ch\u1ee7ng ph\u00e2n l\u1eadp ph\u1ed5 bi\u1ebfn th\u01b0\u1eddng \u0111\u01b0\u1ee3c c\u00e1c ph\u00f2ng th\u00ed nghi\u1ec7m d\u01b0\u1ee3c ph\u1ea9m y\u00eau c\u1ea7u chuy\u1ec3n \u0111\u1ed5i sang \u0111\u1ecbnh d\u1ea1ng <a href=\"https:\/\/gd-1.com\/san-pham\/chung-vi-sinh-dinh-luong-bioball\/\">BIOBALL\u00ae<\/a> nh\u01b0 m\u1ed9t ph\u1ea7n c\u1ee7a <a href=\"https:\/\/gd-1.com\/san-pham\/chung-vi-sinh-dinh-luong-bioball\/\">BIOBALL\u00ae<\/a> c\u1ee7a <a href=\"https:\/\/gd-1.com\/product-brands\/biomerieux\/\">bioM\u00e9rieux<\/a> (H\u00ecnh 2).<\/p>\n<ol>\n<li>Micrococcus luteus v\u00e0 Staphylococcus epidermidis, c\u1ea7u khu\u1ea9n gram d\u01b0\u01a1ng, l\u00e0 nh\u1eefng vi khu\u1ea9n c\u1ed9ng sinh tr\u00ean da ph\u1ed5 bi\u1ebfn nh\u1ea5t \u0111\u01b0\u1ee3c quan s\u00e1t th\u1ea5y trong ph\u00f2ng s\u1ea1ch d\u01b0\u1ee3c ph\u1ea9m do ng\u01b0\u1eddi v\u1eadn h\u00e0nh trong m\u00f4i tr\u01b0\u1eddng.<\/li>\n<li>Bacillus cereus, tr\u1ef1c khu\u1ea9n gram d\u01b0\u01a1ng h\u00ecnh th\u00e0nh b\u00e0o t\u1eed, \u0111\u00e1ng ch\u00fa \u00fd l\u00e0 m\u1ed9t trong nh\u1eefng lo\u00e0i Bacillus \u0111\u01b0\u1ee3c ph\u00e2n l\u1eadp ph\u1ed5 bi\u1ebfn nh\u1ea5t <span style=\"color: #555555;\">trong ph\u00f2ng s\u1ea1ch d\u01b0\u1ee3c ph\u1ea9m. Do t\u00ednh ch\u1ea5t ph\u1ed5 bi\u1ebfn c\u1ee7a n\u00f3, Bacillus cereus h\u00ecnh th\u00e0nh b\u00e0o t\u1eed c\u00f3 nguy c\u01a1 \u0111\u00e1ng k\u1ec3 \u0111\u1ed1i v\u1edbi ch\u1ea5t l\u01b0\u1ee3ng s\u1ea3n ph\u1ea9m v\u00e0 s\u1ef1 an to\u00e0n c\u1ee7a b\u1ec7nh nh\u00e2n, do \u0111\u00f3 c\u1ea7n c\u00f3 ch\u1ebf \u0111\u1ed9 l\u00e0m s\u1ea1ch v\u00e0 kh\u1eed tr\u00f9ng hi\u1ec7u qu\u1ea3, h\u1ec7 th\u1ed1ng x\u1eed l\u00fd kh\u00f4ng kh\u00ed hi\u1ec7u qu\u1ea3 v\u00e0 <\/span><span style=\"color: #555555;\">ch\u01b0\u01a1ng tr\u00ecnh EM m\u1ea1nh m\u1ebd gi\u00e1m s\u00e1t li\u00ean t\u1ee5c c\u00e1c m\u1ed1i lo ng\u1ea1i v\u1ec1 \u00f4 nhi\u1ec5m.<\/span><\/li>\n<li>Ralstonia pickettii, gram \u00e2m oxidase d\u01b0\u01a1ng, l\u00e0 m\u1ed9t trong nh\u1eefng ch\u1ee7ng ph\u00e2n l\u1eadp ph\u1ed5 bi\u1ebfn nh\u1ea5t \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong h\u1ec7 th\u1ed1ng n\u01b0\u1edbc d\u01b0\u1ee3c ph\u1ea9m do kh\u1ea3 n\u0103ng sinh s\u00f4i n\u1ea3y n\u1edf v\u00e0 h\u00ecnh th\u00e0nh m\u00e0ng sinh h\u1ecdc trong \u0111i\u1ec1u ki\u1ec7n dinh d\u01b0\u1ee1ng th\u1ea5p.<\/li>\n<li>N\u1ea5m m\u1ed1c nh\u01b0 Penicillium chrysogenum, l\u00e0 ch\u1ea5t g\u00e2y \u00f4 nhi\u1ec5m n\u1ea5m \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong ph\u00f2ng s\u1ea1ch do thi\u1ebft k\u1ebf k\u00e9m, c\u01a1 s\u1edf v\u1eadt ch\u1ea5t c\u0169 k\u1ef9, ki\u1ec3m so\u00e1t nguy\u00ean li\u1ec7u \u0111\u1ea7u v\u00e0o k\u00e9m v\u00e0 h\u1ec7 th\u1ed1ng x\u1eed l\u00fd kh\u00f4ng kh\u00ed kh\u00f4ng hi\u1ec7u qu\u1ea3.<\/li>\n<\/ol>\n<h2><span class=\"ez-toc-section\" id=\"Ket_luan\"><\/span><strong>K\u1ebft lu\u1eadn<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>D\u1ef1a tr\u00ean c\u00e1c \u00fd ki\u1ebfn ph\u1ed5 bi\u1ebfn, c\u00e1c ch\u1ee7ng ph\u00e2n l\u1eadp n\u1ed9i b\u1ed9 th\u1ef1c s\u1ef1 c\u00f3 m\u1ed9t v\u1ecb tr\u00ed trong vi sinh d\u01b0\u1ee3c ph\u1ea9m mang l\u1ea1i s\u1ef1 tin c\u1eady cao h\u01a1n v\u1ec1 hi\u1ec7u qu\u1ea3 c\u1ee7a m\u00f4i tr\u01b0\u1eddng nu\u00f4i c\u1ea5y v\u00e0 nghi\u00ean c\u1ee9u nh\u1eadn di\u1ec7n vi sinh v\u1eadt. \u0110\u00f3 l\u00e0 khuy\u1ebfn kh\u00edch \u0111\u1ec3 thi\u1ebft l\u1eadp c\u01a1 s\u1edf l\u1ef1a ch\u1ecdn ph\u00e2n l\u1eadp n\u1ed9i b\u1ed9 v\u00e0 ghi l\u1ea1i quy tr\u00ecnh tr\u01b0\u1edbc khi th\u1ef1c hi\u1ec7n c\u00e1c x\u00e9t nghi\u1ec7m vi sinh.<\/p>\n<p>Xem x\u00e9t c\u00e1c th\u00e1ch th\u1ee9c li\u00ean quan \u0111\u1ebfn vi\u1ec7c x\u1eed l\u00fd n\u1ed9i b\u1ed9, <a href=\"https:\/\/gd-1.com\/san-pham\/chung-vi-sinh-dinh-luong-bioball\/\">BIOBALL\u00ae<\/a> gi\u00fap \u0111\u01a1n gi\u1ea3n h\u00f3a vi\u1ec7c qu\u1ea3n l\u00fd c\u00e1ch ly n\u1ed9i b\u1ed9 b\u1eb1ng c\u00e1ch ph\u00e1t tri\u1ec3n ch\u00fang th\u00e0nh \u0111\u1ecbnh d\u1ea1ng <a href=\"https:\/\/gd-1.com\/san-pham\/chung-vi-sinh-dinh-luong-bioball\/\">BIOBALL\u00ae<\/a> s\u1eb5n s\u00e0ng s\u1eed d\u1ee5ng, t\u1eeb \u0111\u00f3 c\u1ea3i thi\u1ec7n hi\u1ec7u qu\u1ea3 ho\u1ea1t \u0111\u1ed9ng v\u00e0 gi\u1ea3m thi\u1ec3u r\u1ee7i ro l\u1ed7i QC.<\/p>\n<p><em>Ngu\u1ed3n: <\/em><\/p>\n<p><em><a href=\"https:\/\/www.biomerieux.com\/content\/dam\/biomerieux-com\/14---resources\/pharma-quality-control\/white-paper\/role-of-in-house-isolates-in-pharmaceutical-quality-control\/EPR%20App%20Note%20-%20Role%20of%20in-house%20isolates%20in%20pharmaceutical%20quality%20control%20-%20VDEF%202023.pdf.coredownload.pdf\" target=\"_blank\" rel=\"noopener\">https:\/\/www.biomerieux.com\/content\/dam\/biomerieux-com\/14&#8212;resources\/pharma-quality-control\/white-paper\/role-of-in-house-isolates-in-pharmaceutical-quality-control\/EPR%20App%20Note%20-%20Role%20of%20in-house%20isolates%20in%20pharmaceutical%20quality%20control%20-%20VDEF%202023.pdf.coredownload.pdf<\/a><\/em><\/p>\n<p><strong>Minh Khang l\u00e0 nh\u00e0 ph\u00e2n ph\u1ed1i \u0111\u1ed9c quy\u1ec1n s\u1ea3n ph\u1ea9m <a href=\"https:\/\/gd-1.com\/product-category\/cong-nghe-sinh-hoc\/vi-sinh-truyen-thong\/chung-vi-sinh\/\">ch\u1ee7ng vi sinh<\/a> h\u00e3ng<a href=\"https:\/\/gd-1.com\/product-brands\/biomerieux\/\">\u00a0bioM\u00e9rieux<\/a>\u00a0(Ph\u00e1p).<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00d4 nhi\u1ec5m VI SINH V\u1eacT trong d\u01b0\u1ee3c ph\u1ea9m \u1ea3nh h\u01b0\u1edfng x\u1ea5u \u0111\u1ebfn hi\u1ec7u qu\u1ea3 v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng c\u1ee7a ch\u00fang, g\u00e2y ra r\u1ee7i ro \u0111\u00e1ng k\u1ec3 cho b\u1ec7nh nh\u00e2n. Chu\u1ea9n b\u1ecb v\u00e0 b\u1ea3o tr\u00ec li\u00ean t\u1ee5c \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o hi\u1ec7u l\u1ef1c v\u00e0 \u0111\u1ed9 an to\u00e0n c\u1ee7a thu\u1ed1c v\u00f4 tr\u00f9ng, b\u1eaft bu\u1ed9c ph\u1ea3i gi\u00e1m s\u00e1t ch\u1ea5t l\u01b0\u1ee3ng&#8230;<\/p>\n","protected":false},"author":3,"featured_media":11298,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"rank_math_lock_modified_date":false,"footnotes":""},"categories":[40],"tags":[],"class_list":["post-11294","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"acf":[],"_links":{"self":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/11294"}],"collection":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/comments?post=11294"}],"version-history":[{"count":7,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/11294\/revisions"}],"predecessor-version":[{"id":11792,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/11294\/revisions\/11792"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/media\/11298"}],"wp:attachment":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/media?parent=11294"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/categories?post=11294"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/tags?post=11294"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}