{"id":12832,"date":"2024-06-11T09:55:14","date_gmt":"2024-06-11T09:55:14","guid":{"rendered":"https:\/\/gd-1.com\/?p=12832"},"modified":"2024-06-11T09:58:14","modified_gmt":"2024-06-11T09:58:14","slug":"ung-dung-ky-thuat-nhuom-ghep-da-kenh-nang-cao-chan-doan-ung-thu","status":"publish","type":"post","link":"https:\/\/gd-1.com\/ung-dung-ky-thuat-nhuom-ghep-da-kenh-nang-cao-chan-doan-ung-thu\/","title":{"rendered":"\u1ee8ng d\u1ee5ng k\u1ef9 thu\u1eadt nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh n\u00e2ng cao ch\u1ea9n \u0111o\u00e1n ung th\u01b0"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_69_1 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<label class=\"ez-toc-title ez-toc-toggle\" style=\"cursor:pointer\">T\u00f3m t\u1eaft n\u1ed9i dung<\/label>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #0a0a0a;color:#0a0a0a\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #0a0a0a;color:#0a0a0a\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/gd-1.com\/ung-dung-ky-thuat-nhuom-ghep-da-kenh-nang-cao-chan-doan-ung-thu\/#Qua_trinh_chan_doan_ung_thu_tu_sinh_thiet_mo\" title=\"Qu\u00e1 tr\u00ecnh ch\u1ea9n \u0111o\u00e1n ung th\u01b0 t\u1eeb sinh thi\u1ebft m\u00f4\">Qu\u00e1 tr\u00ecnh ch\u1ea9n \u0111o\u00e1n ung th\u01b0 t\u1eeb sinh thi\u1ebft m\u00f4<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/gd-1.com\/ung-dung-ky-thuat-nhuom-ghep-da-kenh-nang-cao-chan-doan-ung-thu\/#Xu_huong_nhuom_ghep_da_kenh\" title=\"Xu h\u01b0\u1edbng nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh\">Xu h\u01b0\u1edbng nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/gd-1.com\/ung-dung-ky-thuat-nhuom-ghep-da-kenh-nang-cao-chan-doan-ung-thu\/#Thach_thuc_cua_ky_thuat_ghep_da_kenh_trong_lam_sang\" title=\"Th\u00e1ch th\u1ee9c c\u1ee7a k\u1ef9 thu\u1eadt gh\u00e9p \u0111a k\u00eanh trong l\u00e2m s\u00e0ng\">Th\u00e1ch th\u1ee9c c\u1ee7a k\u1ef9 thu\u1eadt gh\u00e9p \u0111a k\u00eanh trong l\u00e2m s\u00e0ng<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/gd-1.com\/ung-dung-ky-thuat-nhuom-ghep-da-kenh-nang-cao-chan-doan-ung-thu\/#Tam_nhin_cua_ky_thuat_ghep_da_kenh\" title=\"T\u1ea7m nh\u00ecn c\u1ee7a k\u1ef9 thu\u1eadt gh\u00e9p \u0111a k\u00eanh\">T\u1ea7m nh\u00ecn c\u1ee7a k\u1ef9 thu\u1eadt gh\u00e9p \u0111a k\u00eanh<\/a><\/li><\/ul><\/nav><\/div>\n<div class=\"mt-5\">\n<p>M\u1ed9t trong nh\u1eefng c\u1ea3i ti\u1ebfn trong ph\u00e2n t\u00edch m\u00f4 b\u1ec7nh h\u1ecdc hi\u1ec7n nay l\u00e0 k\u1ef9 thu\u1eadt nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh. B\u00e0i vi\u1ebft d\u01b0\u1edbi \u0111\u00e2y s\u1ebd m\u00f4 t\u1ea3 qu\u00e1 tr\u00ecnh ch\u1ea9n \u0111o\u00e1n ung th\u01b0 v\u00e0 n\u00eau r\u00f5 t\u1ea7m quan tr\u1ecdng c\u1ee7a nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n ung th\u01b0.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Qua_trinh_chan_doan_ung_thu_tu_sinh_thiet_mo\"><\/span>Qu\u00e1 tr\u00ecnh ch\u1ea9n \u0111o\u00e1n ung th\u01b0 t\u1eeb sinh thi\u1ebft m\u00f4<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>M\u1eb7c d\u00f9 c\u00e1c b\u1ec7nh ung th\u01b0 ph\u00e1t sinh t\u1eeb m\u1ed7i v\u1ecb tr\u00ed tr\u00ean c\u01a1 th\u1ec3 con ng\u01b0\u1eddi nh\u01b0ng hai kh\u1ed1i u kh\u00f4ng gi\u1ed1ng nhau. Vi\u1ec7c ch\u1ea9n \u0111o\u00e1n ung th\u01b0 ng\u00e0y nay \u0111\u00f2i h\u1ecfi ph\u1ea3i quan s\u00e1t c\u1ea9n th\u1eadn h\u00ecnh th\u00e1i t\u1ebf b\u00e0o v\u00e0 m\u00f4 trong t\u1eebng kh\u1ed1i u. B\u01b0\u1edbc \u0111\u1ea7u ti\u00ean l\u00e0 thu th\u1eadp sinh thi\u1ebft, m\u1ed9t m\u1ea3nh m\u00f4 kh\u1ed1i u \u0111\u1ec3 nh\u00e0 nghi\u00ean c\u1ee9u b\u1ec7nh h\u1ecdc c\u00f3 th\u1ec3 soi t\u1ebf b\u00e0o d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi. Sinh thi\u1ebft c\u00f3 th\u1ec3 bao g\u1ed3m t\u1eeb m\u1ed9t b\u1ed9 s\u01b0u t\u1eadp m\u00f4 r\u1ea5t nh\u1ecf thu \u0111\u01b0\u1ee3c b\u1eb1ng kim cho \u0111\u1ebfn kh\u1ed1i l\u01b0\u1ee3ng r\u1ea5t l\u1edbn \u0111\u01b0\u1ee3c c\u1eaft b\u1ecf do ph\u1eabu thu\u1eadt. Vi\u1ec7c ch\u1ea9n \u0111o\u00e1n kh\u1ed1i u l\u00e0 ung th\u01b0 v\u00e0 lo\u1ea1i n\u00e0o kh\u00f4ng \u0111\u01a1n gi\u1ea3n, m\u00f4 ph\u1ea3i tr\u1ea3i qua h\u00e0ng tr\u0103m b\u01b0\u1edbc ri\u00eang l\u1ebb \u0111\u1ec3 c\u00f3 th\u1ec3 quan s\u00e1t d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi. Ban \u0111\u1ea7u, m\u00f4 \u0111\u01b0\u1ee3c \u201cc\u1ed1 \u0111\u1ecbnh\u201d trong formalin \u0111\u1ec3 b\u1ea3o qu\u1ea3n c\u1ea5u tr\u00fac c\u1ee7a n\u00f3. M\u00f4 c\u1ed1 \u0111\u1ecbnh n\u00e0y sau \u0111\u00f3 \u0111\u01b0\u1ee3c v\u00f9i parafin \u0111\u1ec3 cho ph\u00e9p x\u1eed l\u00fd, l\u01b0u tr\u1eef v\u00e0 x\u1eed l\u00fd \u0111\u01a1n gi\u1ea3n h\u00f3a. Sau \u0111\u00f3, m\u00f4 \u0111\u01b0\u1ee3c c\u1eaft th\u00e0nh c\u00e1c ph\u1ea7n m\u1ecfng v\u00e0 d\u00e1n tr\u00ean c\u00e1c phi\u1ebfn k\u00ednh, sau \u0111\u00f3 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c nhu\u1ed9m m\u00e0u \u0111\u1ec3 minh h\u1ecda c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m ho\u1eb7c ph\u00e2n t\u1eed c\u1ee5 th\u1ec3 trong t\u1ebf b\u00e0o v\u00e0 m\u00f4.<\/p>\n<p>Thu\u1ed1c nhu\u1ed9m \u0111\u1ea7u ti\u00ean th\u01b0\u1eddng l\u00e0 thu\u1ed1c nhu\u1ed9m hematoxylin v\u00e0 eosin (H&amp;E), ban \u0111\u1ea7u \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong ng\u00e0nh d\u1ec7t may. H&amp;E l\u00e0 ch\u1ea5t nhu\u1ed9m 2 m\u00e0u l\u00e0m n\u1ed5i b\u1eadt c\u1ea5u tr\u00fac t\u1ed5ng th\u1ec3 c\u1ee7a t\u1ebf b\u00e0o v\u00e0 l\u00e0 ti\u00eau chu\u1ea9n to\u00e0n c\u1ea7u \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n m\u00f4. Sau \u0111\u00f3, nh\u00e0 nghi\u00ean c\u1ee9u b\u1ec7nh h\u1ecdc s\u1ebd x\u00e1c \u0111\u1ecbnh nh\u1eefng thu\u1ed1c nhu\u1ed9m b\u1ed5 sung n\u00e0o c\u00f3 th\u1ec3 c\u1ea7n thi\u1ebft \u0111\u1ec3 \u0111\u01b0a ra ch\u1ea9n \u0111o\u00e1n. \u0110\u00f3 l\u00e0 ung th\u01b0 bi\u1ec3u m\u00f4, kh\u1ed1i u t\u1ebf b\u00e0o bi\u1ec3u m\u00f4 hay ung th\u01b0 h\u1ea1ch, kh\u1ed1i u t\u1ebf b\u00e0o b\u1ea1ch huy\u1ebft? Nhu\u1ed9m m\u00f4 h\u00f3a \u201c\u0111\u1eb7c bi\u1ec7t\u201d c\u0169ng s\u1eed d\u1ee5ng thu\u1ed1c nhu\u1ed9m d\u1ec7t, nh\u01b0ng c\u00e1c lo\u1ea1i thu\u1ed1c nhu\u1ed9m hi\u1ec7n \u0111\u1ea1i ch\u00ednh s\u1eed d\u1ee5ng \u0111\u1ea7u d\u00f2 ph\u00e2n t\u1eed \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh v\u00e0 d\u00e1n nh\u00e3n c\u00e1c lo\u1ea1i ph\u00e2n t\u1eed c\u1ee5 th\u1ec3 trong m\u00f4: <a href=\"https:\/\/gd-1.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">h\u00f3a m\u00f4 mi\u1ec5n d\u1ecbch (IHC<\/a>) s\u1eed d\u1ee5ng kh\u00e1ng th\u1ec3 \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh protein ho\u1eb7c carbohydrate, trong khi <a href=\"https:\/\/gd-1.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">lai t\u1ea1i ch\u1ed7 (ISH)<\/a> s\u1eed d\u1ee5ng axit nucleic \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh axit nucleic b\u1ed5 sung (DNA ho\u1eb7c RNA).<\/p>\n<p>Ch\u1ea9n \u0111o\u00e1n ung th\u01b0 v\u00e0o n\u0103m 2020 th\u01b0\u1eddng bao g\u1ed3m m\u1ed9t s\u1ed1 v\u1ebft ph\u00e2n t\u1eed \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh lo\u1ea1i kh\u1ed1i u ch\u00ednh x\u00e1c. C\u00f3 th\u1ec3 c\u1ea7n ph\u1ea3i nhu\u1ed9m th\u00eam \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n ho\u00e0n ch\u1ec9nh v\u00e0 d\u1ef1 \u0111o\u00e1n li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb tr\u00fang \u0111\u00edch n\u00e0o c\u00f3 th\u1ec3 mang l\u1ea1i cho b\u1ec7nh nh\u00e2n s\u1ef1 s\u1ed1ng l\u00e2u nh\u1ea5t ho\u1eb7c c\u01a1 h\u1ed9i s\u1ed1ng s\u00f3t cao nh\u1ea5t. V\u00ec nhi\u1ec1u l\u00fd do, bao g\u1ed3m c\u1ea3 3R \u2013 nhanh ch\u00f3ng, tin c\u1eady v\u00e0 ti\u1ebft ki\u1ec7m \u2013 ph\u1ea7n l\u1edbn c\u00e1c thu\u1ed1c nhu\u1ed9m b\u1ed5 sung l\u00e0 \u0111\u01a1n s\u1eafc, \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1eb1ng c\u00e1ch \u00e1p m\u1ed9t \u0111\u1ea7u d\u00f2 duy nh\u1ea5t v\u00e0o m\u1ed9t ph\u1ea7n (l\u00e1t) m\u00f4 ri\u00eang bi\u1ec7t v\u00e0 s\u1eed d\u1ee5ng m\u1ed9t m\u00e0u duy nh\u1ea5t \u0111\u1ec3 h\u00ecnh dung s\u1ef1 ph\u00e2n b\u1ed1 c\u1ee7a n\u00f3 trong m\u00f4. Trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p ph\u1ee9c t\u1ea1p, t\u1ed5ng s\u1ed1 l\u01b0\u1ee3ng nhu\u1ed9m m\u00e0u c\u00f3 th\u1ec3 v\u01b0\u1ee3t qu\u00e1 20, m\u1ed7i lo\u1ea1i nhu\u1ed9m c\u1ea7n m\u1ed9t l\u00e1t m\u00f4 ri\u00eang bi\u1ec7t. M\u1eb7c d\u00f9 c\u00e1c l\u00e1t m\u00f4 r\u1ea5t m\u1ecfng, vi\u1ec7c s\u1eed d\u1ee5ng nhi\u1ec1u l\u00e1t nh\u01b0 v\u1eady c\u00f3 th\u1ec3 g\u00e2y l\u00e3ng ph\u00ed, \u0111\u1eb7c bi\u1ec7t n\u1ebfu m\u00f4 c\u00f2n c\u1ea7n thi\u1ebft cho c\u00e1c x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n kh\u00e1c. B\u00e1c s\u0129 gi\u1ea3i ph\u1eabu b\u1ec7nh sau \u0111\u00f3 ph\u1ea3i\u00a0 t\u1ef1 t\u00edch h\u1ee3p t\u1eebng lo\u1ea1i nhu\u1ed9m m\u00e0u ri\u00eang l\u1ebb \u0111\u1ec3 t\u1ea1o ra h\u00ecnh \u1ea3nh \u0111a m\u00e0u c\u1ee7a kh\u1ed1i u c\u1ee7a b\u1ec7nh nh\u00e2n.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Xu_huong_nhuom_ghep_da_kenh\"><\/span>Xu h\u01b0\u1edbng nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ng\u00e0y nay, nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh th\u01b0\u1eddng \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n trong nghi\u00ean c\u1ee9u \u0111\u1ec3 hi\u1ec3u chi ti\u1ebft v\u1ec1 c\u00e1c m\u1eabu m\u00f4, nh\u01b0ng do s\u1ef1 k\u1ebft h\u1ee3p c\u1ee7a c\u00e1c y\u1ebfu t\u1ed1 k\u1ef9 thu\u1eadt, v\u1eadn h\u00e0nh v\u00e0 t\u00e0i ch\u00ednh n\u00ean hi\u1ebfm khi \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n trong ph\u00f2ng th\u00ed nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n l\u00e2m s\u00e0ng nh\u01b0 m\u1ed9t ph\u1ea7n c\u1ee7a ch\u1ea9n \u0111o\u00e1n ung th\u01b0. <a href=\"https:\/\/www.leicabiosystems.com\/life-sciences-and-research-solutions\/application\/modern-multiplex-staining-solutions-for-the-ihc-research-lab\/\" target=\"_blank\" rel=\"noopener\">Gh\u00e9p \u0111a k\u00eanh<\/a> cung c\u1ea5p nhi\u1ec1u l\u1ee3i th\u1ebf ti\u1ec1m n\u0103ng \u0111\u1ec3 \u0111\u01b0a ra ch\u1ea9n \u0111o\u00e1n ung th\u01b0 bao g\u1ed3m:<\/p>\n<ol>\n<li>B\u1ea3o qu\u1ea3n m\u00f4. Ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 ph\u1ed5i \u0111\u00e3 c\u00f3 nh\u1eefng ti\u1ebfn b\u1ed9 nhanh ch\u00f3ng trong th\u1eadp k\u1ef7 qua, nh\u01b0ng h\u1ea7u h\u1ebft b\u1ec7nh nh\u00e2n ung th\u01b0 ph\u1ed5i kh\u00f4ng th\u1ec3 ph\u1eabu thu\u1eadt khi h\u1ecd b\u1ecb ung th\u01b0. V\u00ec nh\u1eefng l\u00fd do n\u00e0y, ung th\u01b0 ph\u1ed5i th\u01b0\u1eddng \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n b\u1eb1ng sinh thi\u1ebft kim, t\u1ea1o ra m\u1ed9t m\u1eabu r\u1ea5t nh\u1ecf. T\u00ednh \u0111\u1ebfn gi\u1eefa n\u0103m 2020, c\u00f3 ch\u00edn b\u1ea5t th\u01b0\u1eddng ph\u00e2n t\u1eed kh\u00e1c nhau trong b\u1ec7nh ung th\u01b0 ph\u1ed5i li\u00ean quan \u0111\u1ebfn c\u00e1c li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb tr\u00fang \u0111\u00edch, m\u1ed7i lo\u1ea1i y\u00eau c\u1ea7u m\u1ed9t x\u00e9t nghi\u1ec7m ri\u00eang v\u00e0 s\u1eed d\u1ee5ng m\u1ed9t l\u00e1t m\u00f4 ri\u00eang bi\u1ec7t. Ngo\u00e0i ra, m\u1ed9t s\u1ed1 x\u00e9t nghi\u1ec7m y\u00eau c\u1ea7u g\u1eedi m\u1ed9t s\u1ed1 l\u00e1t m\u00f4 \u0111\u1ebfn ph\u00f2ng th\u00ed nghi\u1ec7m tham chi\u1ebfu l\u1edbn ho\u1eb7c c\u01a1 s\u1edf c\u1ed1t l\u00f5i \u0111\u1ec3 th\u1ef1c hi\u1ec7n gi\u1ea3i tr\u00ecnh t\u1ef1 th\u1ebf h\u1ec7 ti\u1ebfp theo (NGS). Vi\u1ec7c \u00e1p d\u1ee5ng ph\u01b0\u01a1ng ph\u00e1p nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n ung th\u01b0 ph\u1ed5i c\u00f3 th\u1ec3 gi\u00fap b\u1ea3o qu\u1ea3n m\u00f4 \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o ch\u1ea9n \u0111o\u00e1n ch\u00ednh x\u00e1c \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n m\u00e0 kh\u00f4ng c\u1ea7n ph\u1ea3i sinh thi\u1ebft l\u1ea1i.<\/li>\n<li>C\u1ea3i thi\u1ec7n \u0111\u1ed9 ch\u00ednh x\u00e1c ch\u1ea9n \u0111o\u00e1n. Ch\u1ea9n \u0111o\u00e1n ung th\u01b0 tuy\u1ebfn ti\u1ec1n li\u1ec7t th\u01b0\u1eddng bao g\u1ed3m vi\u1ec7c ki\u1ec3m tra h\u01a1n ch\u1ee5c m\u1eabu sinh thi\u1ebft b\u1eb1ng kim, ch\u1ea9n \u0111o\u00e1n v\u00e0 l\u1ef1a ch\u1ecdn li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb c\u1ee7a b\u1ec7nh nh\u00e2n ph\u1ee5 thu\u1ed9c r\u1ea5t nhi\u1ec1u v\u00e0o vi\u1ec7c x\u00e1c \u0111\u1ecbnh lo\u1ea1i, m\u1ee9c \u0111\u1ed9 v\u00e0 k\u00edch th\u01b0\u1edbc c\u1ee7a ung th\u01b0 trong su\u1ed1t qu\u00e1 tr\u00ecnh sinh thi\u1ebft. Trong khi m\u1ed9t s\u1ed1 t\u1ebf b\u00e0o ung th\u01b0 tuy\u1ebfn ti\u1ec1n li\u1ec7t c\u00f3 th\u1ec3 d\u1ec5 d\u00e0ng nh\u1eadn ra khi sinh thi\u1ebft th\u00ec nh\u1eefng t\u1ebf b\u00e0o kh\u00e1c c\u00f3 th\u1ec3 c\u00f3 d\u1ea1ng nh\u01b0 t\u1ebf b\u00e0o l\u00e0nh t\u00ednh. K\u1ef9 thu\u1eadt nhu\u1ed9m nhi\u1ec1u l\u1edbp PIN4 k\u1ebft h\u1ee3p c\u00e1c d\u1ea5u hi\u1ec7u trong t\u1ebf b\u00e0o tuy\u1ebfn ti\u1ec1n li\u1ec7t l\u00e0nh t\u00ednh v\u00e0 \u00e1c t\u00ednh \u0111\u1ec3 c\u00f3 th\u1ec3 nh\u00ecn th\u1ea5y c\u1ea3 hai lo\u1ea1i t\u1ebf b\u00e0o trong c\u00f9ng m\u1ed9t ph\u1ea7n b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng c\u00e1c m\u00e0u s\u1eafc kh\u00e1c nhau, gi\u00fap nh\u00e0 nghi\u00ean c\u1ee9u b\u1ec7nh h\u1ecdc ch\u1ea9n \u0111o\u00e1n ung th\u01b0 tuy\u1ebfn ti\u1ec1n li\u1ec7t m\u1ed9t c\u00e1ch \u0111\u00e1ng tin c\u1eady<\/li>\n<li>N\u00e2ng cao c\u00e1i nh\u00ecn s\u00e2u s\u1eafc ch\u1ea9n \u0111o\u00e1n. Khi ch\u00fang ta t\u00ecm hi\u1ec3u th\u00eam v\u1ec1 c\u00e1ch c\u00e1c kh\u1ed1i u ph\u00e1t tri\u1ec3n v\u00e0 c\u00e1ch c\u00e1c li\u1ec7u ph\u00e1p m\u1edbi c\u00f3 th\u1ec3 ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a ch\u00fang, gh\u00e9p \u0111a k\u00eanh s\u1ebd l\u00e0 m\u1ed9t k\u1ef9 thu\u1eadt thi\u1ebft y\u1ebfu \u0111\u1ec3 h\u00ecnh dung c\u00e1c y\u1ebfu t\u1ed1 n\u00e0y trong m\u1ed7i kh\u1ed1i u. V\u00ed d\u1ee5, m\u1ed9t th\u1ebf h\u1ec7 thu\u1ed1c m\u1edbi, ch\u1ea5t \u1ee9c ch\u1ebf \u0111i\u1ec3m ki\u1ec3m so\u00e1t mi\u1ec5n d\u1ecbch, ng\u0103n ch\u1eb7n kh\u1ea3 n\u0103ng c\u1ee7a kh\u1ed1i u nh\u1eb1m ng\u0103n h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a b\u1ec7nh nh\u00e2n ch\u1ed1ng l\u1ea1i kh\u1ed1i u. M\u1eb7c d\u00f9 v\u1eabn c\u00f2n nhi\u1ec1u \u0111i\u1ec1u c\u1ea7n t\u00ecm hi\u1ec3u nh\u01b0ng ng\u01b0\u1eddi ta ng\u00e0y c\u00e0ng nh\u1eadn ra r\u1eb1ng c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m c\u1ee7a c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch kh\u00e1c nhau trong kh\u1ed1i u, bao g\u1ed3m c\u1ea3 v\u1ecb tr\u00ed v\u00e0 tr\u1ea1ng th\u00e1i k\u00edch ho\u1ea1t c\u1ee7a ch\u00fang, \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1ch th\u1ee9c ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf \u0111i\u1ec3m ki\u1ec3m so\u00e1t. V\u00ed d\u1ee5, c\u00e1c t\u1ebf b\u00e0o lympho trong kh\u1ed1i u c\u00f3 th\u1ec3 \u1edf tr\u1ea1ng th\u00e1i \u201ck\u00edch ho\u1ea1t\u201d ho\u1eb7c \u201cbi\u1ec7t h\u00f3a\u201d, m\u1ed7i tr\u1ea1ng th\u00e1i n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c nh\u00ecn th\u1ea5y trong m\u1ed7i t\u1ebf b\u00e0o b\u1eb1ng c\u00e1ch bi\u1ec3u hi\u1ec7n c\u00e1c protein v\u1edbi m\u00e0u nhu\u1ed9m kh\u00e1c nhau . C\u00e1c kh\u1ed1i u th\u01b0\u1eddng thu h\u00fat c\u00e1c t\u1ebf b\u00e0o kh\u00f4ng ph\u1ea3i kh\u1ed1i u \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 t\u1ebf b\u00e0o \u1ee9c ch\u1ebf b\u1eaft ngu\u1ed3n t\u1eeb myeloid (MDSC) \u0111\u1ec3 ng\u0103n ch\u1eb7n ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch ch\u1ed1ng kh\u1ed1i u t\u1ea1i c\u1ee5m u. Cu\u1ed1i c\u00f9ng, ph\u1ea7n l\u1edbn \u0111\u00e3 \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u v\u1ec1 c\u00e1ch c\u00e1c qu\u1ea7n th\u1ec3 \u0111\u1ea1i th\u1ef1c b\u00e0o kh\u00e1c nhau, c\u00e1c t\u1ebf b\u00e0o bi\u1ec7t h\u00f3a c\u1ee7a c\u01a1 th\u1ec3, c\u00f3 th\u1ec3 h\u1ed7 tr\u1ee3 v\u00e0 do \u0111\u00f3 \u0111\u00f3ng vai tr\u00f2 tr\u00e1i ng\u01b0\u1ee3c nhau trong s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a kh\u1ed1i u. Trong khi hai ch\u1ee9c n\u0103ng n\u00e0y \u0111\u01b0\u1ee3c quy cho hai lo\u1ea1i \u0111\u1ea1i th\u1ef1c b\u00e0o, \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 M1 ho\u1eb7c M2, nh\u1eefng quan s\u00e1t g\u1ea7n \u0111\u00e2y cho th\u1ea5y kh\u00f4ng ph\u1ea3i hai m\u00e0 l\u00e0 ch\u00edn lo\u1ea1i \u0111\u1ea1i th\u1ef1c b\u00e0o kh\u00e1c nhau trong c\u01a1 th\u1ec3! Hi\u1ec7n t\u1ea1i, kh\u00f4ng c\u00f3 quan s\u00e1t n\u00e0o trong s\u1ed1 n\u00e0y \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong ch\u1ea9n \u0111o\u00e1n th\u01b0\u1eddng quy cho b\u1ec7nh nh\u00e2n ung th\u01b0 v\u00ec ch\u00fang ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 c\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ti\u00ean l\u01b0\u1ee3ng ho\u1eb7c l\u1ef1a ch\u1ecdn li\u1ec7u ph\u00e1p, nh\u01b0ng nghi\u00ean c\u1ee9u ph\u1ed5 bi\u1ebfn g\u1ea7n \u0111\u00e2y cho ch\u00fang ta bi\u1ebft ch\u00fang c\u1ef1c k\u1ef3 quan tr\u1ecdng.<\/li>\n<\/ol>\n<p>H\u00e3y xem x\u00e9t t\u00ednh \u0111\u01a1n gi\u1ea3n c\u1ee7a ph\u01b0\u01a1ng ph\u00e1p ti\u1ebfp c\u1eadn ch\u1ea9n \u0111o\u00e1n ung th\u01b0 hi\u1ec7n nay li\u00ean quan \u0111\u1ebfn \u0111\u1ed9 ph\u1ee9c t\u1ea1p tuy\u1ec7t \u0111\u1ed1i c\u1ee7a m\u00f4 ung th\u01b0. C\u00f3 th\u1ec3 th\u1ea5y, \u0111\u1ed9 ph\u1ee9c t\u1ea1p c\u1ee7a m\u1ed9t t\u1ebf b\u00e0o \u0111\u01a1n l\u1ebb, c\u00f3 \u0111\u01b0\u1eddng k\u00ednh ch\u1ec9 b\u1eb1ng 1\/100 milimet. M\u1ed7i t\u1ebf b\u00e0o ng\u01b0\u1eddi b\u00ecnh th\u01b0\u1eddng ch\u1ee9a kho\u1ea3ng hai th\u01b0\u1edbc DNA, ba t\u1ef7 c\u1eb7p baz\u01a1, m\u00e3 h\u00f3a ~21.000 gen, m\u1ed7i gen c\u00f3 th\u1ec3 t\u1ea1o ra nhi\u1ec1u RNA kh\u00e1c nhau. Trong m\u1ed9t t\u1ebf b\u00e0o \u0111i\u1ec3n h\u00ecnh t\u1ea1i b\u1ea5t k\u1ef3 th\u1eddi \u0111i\u1ec3m n\u00e0o c\u0169ng c\u00f3 h\u01a1n m\u1ed9t tri\u1ec7u RNA \u0111i\u1ec1u khi\u1ec3n qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p h\u00e0ng tri\u1ec7u ph\u00e2n t\u1eed protein. Ung th\u01b0 l\u00e0 c\u0103n b\u1ec7nh t\u1eeb DNA; nh\u1eefng thay \u0111\u1ed5i trong DNA g\u00e2y ra nh\u1eefng thay \u0111\u1ed5i v\u1ec1 protein l\u00e0m thay \u0111\u1ed5i c\u1ea5u tr\u00fac t\u1ebf b\u00e0o c\u0169ng nh\u01b0 ch\u1ee9c n\u0103ng c\u1ee7a c\u00e1c c\u01a1 quan trong t\u1ebf b\u00e0o kh\u1ed1i u d\u1eabn \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n kh\u00f4ng ki\u1ec3m so\u00e1t c\u1ee7a kh\u1ed1i u.<\/p>\n<p>C\u00e1c t\u1ebf b\u00e0o ung th\u01b0 bi\u1ec3u hi\u1ec7n nhi\u1ec1u b\u1ea5t th\u01b0\u1eddng, ph\u1ee9c t\u1ea1p v\u00e0 kh\u00f4ng \u0111\u1ed3ng nh\u1ea5t h\u01a1n nhi\u1ec1u so v\u1edbi c\u00e1c t\u1ebf b\u00e0o kh\u00f4ng ung th\u01b0. Tuy nhi\u00ean, v\u00e0o n\u0103m 2020 \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n ung th\u01b0,<a href=\"https:\/\/www.leicabiosystems.com\/\" target=\"_blank\" rel=\"noopener\"> Leica Biosytems<\/a> v\u1eabn ch\u1ec9 ki\u1ec3m tra m\u1ed9t lo\u1ea1i ph\u00e2n t\u1eed (axit nucleic ho\u1eb7c protein) trong m\u1ed7i ph\u1ea7n m\u00f4. C\u00e1c k\u1ef9 thu\u1eadt nghi\u00ean c\u1ee9u ph\u1ed5 bi\u1ebfn li\u00ean quan \u0111\u1ebfn vi\u1ec7c ph\u00e1t hi\u1ec7n c\u00e1c d\u1ea5u hi\u1ec7u b\u1eb1ng hu\u1ef3nh quang ho\u1eb7c kh\u1ed1i ph\u1ed5 c\u00f3 th\u1ec3 t\u0103ng s\u1ed1 l\u01b0\u1ee3ng ph\u00e2n t\u1eed quan s\u00e1t \u0111\u01b0\u1ee3c c\u00f9ng m\u1ed9t l\u00fac l\u00ean g\u1ea5p 10 l\u1ea7n so v\u1edbi c\u00e1c k\u1ef9 thu\u1eadt truy\u1ec1n th\u1ed1ng v\u00e0 k\u1ef9 thu\u1eadt ph\u00e2n t\u00edch t\u1ebf b\u00e0o \u0111\u01a1n c\u00f3 th\u1ec3 \u0111\u1ecbnh l\u01b0\u1ee3ng h\u00e0ng ngh\u00ecn ph\u00e2n t\u1eed kh\u00e1c nhau trong m\u1ed7i t\u1ebf b\u00e0o. L\u01b0\u1ee3ng d\u1eef li\u1ec7u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c tr\u00edch xu\u1ea5t t\u1eeb \u200b\u200b\u200b\u200bm\u1ed9t kh\u1ed1i u l\u00e0 r\u1ea5t l\u1edbn, tuy nhi\u00ean h\u1ea7u h\u1ebft d\u1eef li\u1ec7u \u0111\u00f3 \u0111\u1ec1u kh\u00f4ng li\u00ean quan \u0111\u1ebfn ch\u1ea9n \u0111o\u00e1n c\u1ee7a b\u1ec7nh nh\u00e2n. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u b\u1ec7nh h\u1ecdc tin r\u1eb1ng \u0111i\u1ec1u quan tr\u1ecdng l\u00e0 ph\u1ea3i quan s\u00e1t c\u00e1c ph\u00e2n t\u1eed trong c\u00e1c ph\u1ea7n m\u00f4 \u0111\u1ec3 \u0111\u01b0a ra ch\u1ea9n \u0111o\u00e1n t\u1ed1t nh\u1ea5t. Gh\u00e9p \u0111a k\u00eanh c\u00f3 th\u1ec3 gi\u1ea3i quy\u1ebft v\u1ea5n \u0111\u1ec1 hi\u1ec3n th\u1ecb \u0111\u00fang t\u1eadp h\u1ee3p ph\u00e2n t\u1eed trong ph\u1ea7n m\u00f4 c\u1ee7a m\u1ed7i b\u1ec7nh nh\u00e2n.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Thach_thuc_cua_ky_thuat_ghep_da_kenh_trong_lam_sang\"><\/span>Th\u00e1ch th\u1ee9c c\u1ee7a k\u1ef9 thu\u1eadt gh\u00e9p \u0111a k\u00eanh trong l\u00e2m s\u00e0ng<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh c\u0169ng c\u00f3 r\u00e0o c\u1ea3n \u0111\u1ed1i v\u1edbi vi\u1ec7c th\u1ef1c hi\u1ec7n ch\u0103m s\u00f3c l\u00e2m s\u00e0ng, bao g\u1ed3m nhu c\u1ea7u x\u00e1c nh\u1eadn x\u00e9t nghi\u1ec7m r\u1ed9ng r\u00e3i, t\u0103ng th\u1eddi gian ch\u1ea1y x\u00e9t nghi\u1ec7m, chi ph\u00ed thu\u1ed1c th\u1eed so v\u1edbi s\u1ed1 l\u01b0\u1ee3ng thu\u1ed1c nhu\u1ed9m \u0111\u01a1n s\u1eafc t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u00e0 s\u1ef1 h\u1ea1n ch\u1ebf k\u1ef9 thu\u1eadt vi\u00ean c\u00f3 k\u1ef9 n\u0103ng th\u1ef1c hi\u1ec7n v\u00e0 gi\u1ea3i th\u00edch c\u00e1c x\u00e9t nghi\u1ec7m. Qu\u00e1 tr\u00ecnh x\u00e1c th\u1ef1c c\u1ee7a k\u1ef9 thu\u1eadt gh\u00e9p \u0111a k\u00eanh ph\u1ea3i bao g\u1ed3m so s\u00e1nh v\u1edbi th\u00ed nghi\u1ec7m monoplex, \u0111i\u1ec1u n\u00e0y kh\u00f4ng ch\u1ec9 \u0111\u00f2i h\u1ecfi c\u00e1c y\u00eau c\u1ea7u x\u00e1c th\u1ef1c t\u0103ng l\u00ean m\u00e0 c\u00f2n \u0111\u00f2i h\u1ecfi c\u00e1c gi\u1ea3i ph\u00e1p k\u1ef9 thu\u1eadt s\u1ed1 v\u00e0 t\u00ednh to\u00e1n \u0111\u1ec3 lo\u1ea1i b\u1ecf l\u1ed7i. Trong khi\u00a0 c\u00e1c x\u00e9t nghi\u1ec7m <a style=\"font-size: 14.4px;\" href=\"https:\/\/gd-1.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">IHC&amp;ISH <\/a><span style=\"color: #555555; font-size: 14.4px;\">l\u1ea7n \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n th\u1ee7 c\u00f4ng, s\u1ef1 ra \u0111\u1eddi c\u1ee7a m\u00e1y nhu\u1ed9m robot t\u1ef1 \u0111\u1ed9ng v\u00e0o nh\u1eefng n\u0103m 1990 \u0111\u00e3 l\u00e0m gi\u1ea3m th\u1eddi gian th\u1ef1c hi\u1ec7n x\u00e9t nghi\u1ec7m \u0111\u1ed3ng th\u1eddi c\u1ea3i thi\u1ec7n kh\u1ea3 n\u0103ng t\u00e1i l\u1eadp. C\u00e1c giao th\u1ee9c nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh t\u1ef1 \u0111\u1ed9ng hi\u1ec7n t\u1ea1i th\u01b0\u1eddng m\u1ea5t nhi\u1ec1u th\u1eddi gian h\u01a1n so v\u1edbi c\u00e1c quy tr\u00ecnh nhu\u1ed9m \u0111\u01a1n s\u1eafc t\u01b0\u01a1ng \u0111\u01b0\u01a1ng. Chi ph\u00ed thu\u1ed1c th\u1eed v\u1eabn l\u00e0 m\u1ed9t th\u00e1ch th\u1ee9c, m\u1eb7c d\u00f9 <\/span><a style=\"font-size: 14.4px;\" href=\"https:\/\/www.leicabiosystems.com\/\" target=\"_blank\" rel=\"noopener\">Leica Biosystems<\/a><span style=\"color: #555555; font-size: 14.4px;\"> d\u1ef1 \u0111o\u00e1n vi\u1ec7c \u00e1p d\u1ee5ng r\u1ed9ng r\u00e3i h\u01a1n s\u1ebd gi\u1ea3m chi ph\u00ed v\u1ec1 l\u00e2u d\u00e0i.<\/span><\/p>\n<p><em>Gh\u00e9p \u0111a k\u00eanh c\u00f3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1eb1ng b\u1ec7nh l\u1ef9 k\u1ef9 thu\u1eadt s\u1ed1 kh\u00f4ng?<\/em><\/p>\n<p>Ngo\u00e0i ra c\u00f2n c\u00f3 nh\u1eefng th\u00e1ch th\u1ee9c xung quanh vi\u1ec7c gi\u1ea3i th\u00edch th\u00ed nghi\u1ec7m t\u0103ng theo s\u1ed1 l\u01b0\u1ee3ng \u0111i\u1ec3m \u0111\u01b0\u1ee3c \u0111o t\u1ea1i m\u1ed9t th\u1eddi \u0111i\u1ec3m. B\u1edfi v\u00ec c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u b\u1ec7nh h\u1ecdc \u0111\u00e3 quen v\u1edbi vi\u1ec7c gi\u1ea3i th\u00edch c\u00e1c v\u1ebft nhu\u1ed9m \u0111\u01a1n th\u01b0\u1eddng d\u00e1n nh\u00e3n cho m\u1ed9t lo\u1ea1i t\u1ebf b\u00e0o ho\u1eb7c ng\u0103n m\u00f4, n\u00ean vi\u1ec7c gi\u1ea3i th\u00edch v\u1ebft nhu\u1ed9m hai \u0111i\u1ec3m \u0111\u00e1nh d\u1ea5u ho\u1eb7c v\u1ebft triplex (ba \u0111i\u1ec3m \u0111\u00e1nh d\u1ea5u) th\u01b0\u1eddng kh\u00f4ng kh\u00f3 h\u01a1n vi\u1ec7c gi\u1ea3i th\u00edch m\u1ed9t t\u1eadp h\u1ee3p c\u00e1c v\u1ebft \u0111\u01a1n ph\u1ee9c n\u1ebfu m\u1ed7i v\u1ebft \u0111\u00e1nh d\u1ea5u kh\u00f4ng b\u1ecb ch\u1ed3ng ch\u00e9o l\u00ean nhau. Trong nhi\u1ec1u tr\u01b0\u1eddng h\u1ee3p, vi\u1ec7c quan s\u00e1t \u0111\u1ed3ng th\u1eddi hai ho\u1eb7c nhi\u1ec1u \u0111i\u1ec3m \u0111\u00e1nh d\u1ea5u trong c\u00f9ng m\u1ed9t ph\u1ea7n s\u1ebd mang l\u1ea1i gi\u00e1 tr\u1ecb gia t\u0103ng. Tuy nhi\u00ean, n\u1ebfu c\u00f3 hai ho\u1eb7c nhi\u1ec1u ph\u00e2n t\u1eed hi\u1ec7n di\u1ec7n trong c\u00f9ng m\u1ed9t ng\u0103n ho\u1eb7c m\u00f4 t\u1ebf b\u00e0o v\u00e0 s\u1ed1 l\u01b0\u1ee3ng ph\u00e2n t\u1eed trong t\u1ebf b\u00e0o l\u00e0 quan tr\u1ecdng \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 tr\u1ea1ng th\u00e1i c\u1ee7a n\u00f3. H\u00e3y h\u00ecnh dung 30 ho\u1eb7c 3000 ph\u00e2n t\u1eed tr\u00ean m\u1ed7i t\u1ebf b\u00e0o! R\u00f5 r\u00e0ng, c\u1ea7n c\u00f3 c\u00e1c ch\u01b0\u01a1ng tr\u00ecnh m\u00e1y t\u00ednh gi\u00fap ph\u00e2n t\u00edch h\u00ecnh \u1ea3nh \u0111\u1ec3 gi\u1ea3i th\u00edch. Ng\u00e0y nay, ch\u00fang ta \u0111ang nhanh ch\u00f3ng b\u01b0\u1edbc v\u00e0o th\u1eddi \u0111\u1ea1i \u201cb\u1ec7nh l\u00fd k\u1ef9 thu\u1eadt s\u1ed1\u201d, trong \u0111\u00f3 vi\u1ec7c gi\u1ea3i th\u00edch c\u00e1c m\u00f4 c\u1ee7a b\u1ec7nh nh\u00e2n s\u1ebd t\u1ed1i \u01b0u h\u01a1n l\u00e0 b\u1eb1ng k\u00ednh hi\u1ec3n vi truy\u1ec1n th\u1ed1ng. V\u1edbi vi\u1ec7c \u00e1p d\u1ee5ng b\u1ec7nh l\u00fd k\u1ef9 thu\u1eadt s\u1ed1 s\u1ebd xu\u1ea5t hi\u1ec7n c\u00e1c \u201c\u1ee9ng d\u1ee5ng\u201d bao g\u1ed3m \u0111\u1ecbnh l\u01b0\u1ee3ng ph\u00e2n t\u1eed v\u00e0 tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o s\u1ebd gi\u00fap nh\u00e0 nghi\u00ean c\u1ee9u b\u1ec7nh h\u1ecdc gi\u1ea3i th\u00edch c\u00e1c b\u1ed9 d\u1eef li\u1ec7u ph\u1ee9c t\u1ea1p m\u00e0 c\u00e1c v\u1ebft nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh c\u00f3 th\u1ec3 t\u1ea1o ra.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Tam_nhin_cua_ky_thuat_ghep_da_kenh\"><\/span>T\u1ea7m nh\u00ecn c\u1ee7a k\u1ef9 thu\u1eadt gh\u00e9p \u0111a k\u00eanh<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Nh\u1eefng ti\u1ebfn b\u1ed9 trong \u0111i\u1ec1u tr\u1ecb ung th\u01b0 ng\u00e0y c\u00e0ng li\u00ean quan \u0111\u1ebfn nh\u1eefng b\u1ea5t th\u01b0\u1eddng v\u1ec1 ph\u00e2n t\u1eed c\u1ee5 th\u1ec3 trong b\u1ec7nh ung th\u01b0 c\u1ee7a m\u1ed7i b\u1ec7nh nh\u00e2n, \u0111i\u1ec1u n\u00e0y d\u1eabn \u0111\u1ebfn qu\u00e1 tr\u00ecnh sinh thi\u1ebft c\u1ee7a m\u1ed7i b\u1ec7nh nh\u00e2n tr\u1edf n\u00ean ph\u1ee9c t\u1ea1p h\u01a1n. Khi s\u1ed1 l\u01b0\u1ee3ng ph\u00e2n t\u1eed c\u1ea7n \u0111i\u1ec1u tra trong sinh thi\u1ebft ung th\u01b0 ti\u1ebfp t\u1ee5c t\u0103ng, <a href=\"https:\/\/www.leicabiosystems.com\/\" target=\"_blank\" rel=\"noopener\">Leica Biosystems<\/a> tin r\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p gh\u00e9p \u0111a k\u00eanh s\u1ebd \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong ph\u00e2n t\u00edch sinh thi\u1ebft b\u1eb1ng c\u00e1ch t\u1ed1i \u0111a h\u00f3a vi\u1ec7c s\u1eed d\u1ee5ng m\u00f4 h\u1ea1n ch\u1ebf, c\u1ea3i thi\u1ec7n \u0111\u1ed9 ch\u00ednh x\u00e1c ch\u1ea9n \u0111o\u00e1n v\u00e0 n\u00e2ng cao hi\u1ec3u bi\u1ebft s\u00e2u s\u1eafc v\u1ec1 ch\u1ea9n \u0111o\u00e1n, c\u0169ng nh\u01b0 \u0111\u00f3ng vai tr\u00f2 l\u00e0 c\u00f4ng c\u1ee5 d\u1ef1 \u0111o\u00e1n t\u1ed1t h\u01a1n v\u1ec1 ti\u00ean l\u01b0\u1ee3ng v\u00e0 h\u01b0\u1edbng d\u1eabn l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb. Ngo\u00e0i nh\u1eefng ti\u1ebfn b\u1ed9 trong c\u00f4ng ngh\u1ec7 nhu\u1ed9m m\u00e0u, vi\u1ec7c \u00e1p d\u1ee5ng \u0111\u1ea7y \u0111\u1ee7 c\u00f4ng ngh\u1ec7 gh\u00e9p \u0111a k\u00eanh s\u1ebd \u0111\u00f2i h\u1ecfi c\u00e1c c\u00f4ng c\u1ee5 k\u1ef9 thu\u1eadt s\u1ed1, t\u00ednh to\u00e1n v\u00e0 cu\u1ed1i c\u00f9ng l\u00e0 tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o \u0111\u1ec3 h\u1ed7 tr\u1ee3 c\u00e1c ch\u1ea9n \u0111o\u00e1n v\u00e0 c\u00e1c li\u1ec7u ph\u00e1p c\u00e1 nh\u00e2n h\u00f3a.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright\" src=\"https:\/\/www.leicabiosystems.com\/sites\/default\/files\/styles\/720_tablet_portrait_fallback\/public\/media_image-file\/2022-02\/csm_image1_aa06d44e59.jpg?itok=yt2Vlxkr\" alt=\"Gi\u00e1 tr\u1ecb c\u1ee7a nhu\u1ed9m Multiplex trong ch\u1ea9n \u0111o\u00e1n ung th\u01b0\" width=\"414\" height=\"234\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft\" src=\"https:\/\/www.leicabiosystems.com\/sites\/default\/files\/styles\/720_tablet_portrait_fallback\/public\/media_image-file\/2022-02\/csm_image2_092a551910.jpg?itok=cqoQiCMC\" alt=\"H\u00ecnh 1B Gi\u00e1 tr\u1ecb c\u1ee7a nhu\u1ed9m multiplex\" width=\"401\" height=\"226\" \/><\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<div class=\"mt-5\">\n<p>Ngu\u1ed3n: <a href=\"https:\/\/www.leicabiosystems.com\/knowledge-pathway\/the-value-of-multiplex-staining-in-the-diagnosis-of-cancer\/\" target=\"_blank\" rel=\"noopener\">https:\/\/www.leicabiosystems.com\/knowledge-pathway\/the-value-of-multiplex-staining-in-the-diagnosis-of-cancer\/<\/a><\/p>\n<p><strong>Minh Khang l\u00e0 nh\u00e0 ph\u00e2n ph\u1ed1i v\u00e0 nh\u1eadp kh\u1ea9u tr\u1ef1c ti\u1ebfp c\u00e1c thi\u1ebft b\u1ecb\u00a0<a href=\"https:\/\/www.leicabiosystems.com\/en-sg\/\" target=\"_blank\" rel=\"noopener\">Gi\u1ea3i ph\u1eabu b\u1ec7nh<\/a>\u00a0t\u1eeb h\u00e3ng\u00a0<a href=\"https:\/\/www.leicabiosystems.com\/\" target=\"_blank\" rel=\"noopener\">Leica Biosystems<\/a>.<\/strong><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>M\u1ed9t trong nh\u1eefng c\u1ea3i ti\u1ebfn trong ph\u00e2n t\u00edch m\u00f4 b\u1ec7nh h\u1ecdc hi\u1ec7n nay l\u00e0 k\u1ef9 thu\u1eadt nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh. B\u00e0i vi\u1ebft d\u01b0\u1edbi \u0111\u00e2y s\u1ebd m\u00f4 t\u1ea3 qu\u00e1 tr\u00ecnh ch\u1ea9n \u0111o\u00e1n ung th\u01b0 v\u00e0 n\u00eau r\u00f5 t\u1ea7m quan tr\u1ecdng c\u1ee7a nhu\u1ed9m gh\u00e9p \u0111a k\u00eanh \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n ung th\u01b0. Qu\u00e1 tr\u00ecnh ch\u1ea9n \u0111o\u00e1n ung th\u01b0&#8230;<\/p>\n","protected":false},"author":3,"featured_media":12833,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"rank_math_lock_modified_date":false,"footnotes":""},"categories":[40],"tags":[],"class_list":["post-12832","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"acf":[],"_links":{"self":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/12832"}],"collection":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/comments?post=12832"}],"version-history":[{"count":7,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/12832\/revisions"}],"predecessor-version":[{"id":12837,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/12832\/revisions\/12837"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/media\/12833"}],"wp:attachment":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/media?parent=12832"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/categories?post=12832"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/tags?post=12832"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}