V\u1eafc-xin t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng ng\u00e0y c\u00e0ng t\u0103ng, \u0111i\u1ec1u n\u00e0y th\u00fac \u0111\u1ea9y nhu c\u1ea7u v\u1ec1 c\u00e1c s\u1ea3n ph\u1ea9m v\u1eafc-xin ng\u00e0y c\u00e0ng cao h\u01a1n, t\u1eeb ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi cho b\u1ec7nh ung th\u01b0 v\u00e0 c\u00fam theo m\u00f9a, \u0111\u1ebfn ng\u0103n ch\u1eb7n c\u00e1c m\u1ed1i \u0111e d\u1ecda kh\u1ee7ng b\u1ed1 sinh h\u1ecdc v\u00e0 c\u00e1c b\u1ec7nh truy\u1ec1n nhi\u1ec5m m\u1edbi n\u1ed5i. Beckman Coulter, Inc. cung c\u1ea5p \u0111\u1ea7y \u0111\u1ee7 c\u00e1c s\u1ea3n ph\u1ea9m li\u00ean quan \u0111\u1ebfn thi\u1ebft b\u1ecb ly t\u00e2m<\/a> \u0111\u1ec3 t\u0103ng c\u01b0\u1eddng ph\u00e1t tri\u1ec3n v\u00e0 s\u1ea3n xu\u1ea5t v\u1eafc-xin. T\u1eeb vi\u1ec7c l\u00e0m s\u1ea1ch t\u1ebf b\u00e0o ban \u0111\u1ea7u \u0111\u1ebfn tinh ch\u1ebf ho\u1eb7c ph\u00e2n t\u00e1ch virus b\u1ea5t ho\u1ea1t, Beckman Coulter, Inc. cung c\u1ea5p c\u00e1c thi\u1ebft b\u1ecb ly t\u00e2m<\/a> l\u00fd t\u01b0\u1edfng cho ph\u00f2ng th\u00ed nghi\u1ec7m c\u1ee7a b\u1ea1n. D\u1ef1a tr\u00ean kinh nghi\u1ec7m h\u01a1n 6 th\u1eadp k\u1ef7, to\u00e0n b\u1ed9 d\u00f2ng s\u1ea3n ph\u1ea9m ly t\u00e2m \u0111\u00e3 mang \u0111\u1ebfn qu\u00e1 tr\u00ecnh ph\u00e2n t\u00e1ch ch\u1ea5t l\u01b0\u1ee3ng trong th\u1eddi gian ng\u1eafn. Cho d\u00f9 b\u1ea1n \u0111ang t\u1eadp trung v\u00e0o v\u1eafc-xin vi-r\u00fat, vi khu\u1ea9n hay v\u1eafc-xin d\u1ef1a tr\u00ean t\u1ebf b\u00e0o, c\u00f4ng ngh\u1ec7 ly t\u00e2m s\u1ebd t\u0103ng t\u1ed1c c\u00e1c quy tr\u00ecnh c\u1ee7a b\u1ea1n, c\u1ea3i thi\u1ec7n n\u0103ng su\u1ea5t v\u00e0 cho ph\u00e9p \u0111\u1ea1t \u0111\u01b0\u1ee3c c\u00e1c m\u1ee5c ti\u00eau ph\u00e1t tri\u1ec3n v\u00e0 s\u1ea3n xu\u1ea5t \u0111\u00f2i h\u1ecfi kh\u1eaft khe. Ngo\u00e0i thi\u1ebft b\u1ecb ly t\u00e2m<\/a>, Beckman Coulter c\u00f2n cung c\u1ea5p c\u00e1c gi\u1ea3i ph\u00e1p b\u1ed5 sung cho m\u00f4i tr\u01b0\u1eddng v\u1eafc-xin, bao g\u1ed3m m\u00e1y ph\u00e2n t\u00edch kh\u1ea3 n\u0103ng s\u1ed1ng c\u1ee7a t\u1ebf b\u00e0o t\u1ef1 \u0111\u1ed9ng, gi\u1ea3i ph\u00e1p t\u1ebf b\u00e0o h\u1ecdc d\u00f2ng ch\u1ea3y v\u00e0 h\u1ec7 th\u1ed1ng m\u00f4 t\u1ea3 \u0111\u1eb7c t\u00ednh protein. H\u00e3y l\u1ef1a ch\u1ecdn Beckman Coulter \u0111\u1ec3 t\u1ea1o ra v\u00e0 cung c\u1ea5p c\u00e1c s\u1ea3n ph\u1ea9m v\u1eafc xin ch\u1ea5t l\u01b0\u1ee3ng cao!<\/p>\n

<\/span>Hi\u1ec7u su\u1ea5t<\/strong><\/span><\/h2>\n
C\u00e1c thi\u1ebft b\u1ecb, rotors, \u1ed1ng, chai v\u00e0 adapters \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u1ec3 ho\u1ea1t \u0111\u1ed9ng c\u00f9ng nhau nh\u01b0 m\u1ed9t h\u1ec7 th\u1ed1ng to\u00e0n di\u1ec7n. C\u00e1ch ti\u1ebfp c\u1eadn theo m\u00f4-\u0111un \u0111\u00e1p \u1ee9ng c\u00e1c v\u1ea5n \u0111\u1ec1 l\u00e2y nhi\u1ec5m ch\u00e9o b\u1eb1ng c\u00e1ch cung c\u1ea5p kh\u1ea3 n\u0103ng so s\u00e1nh gi\u1eefa c\u00e1c l\u00f4, cho ph\u00e9p th\u1eddi gian \u0111\u01b0a s\u1ea3n ph\u1ea9m ra th\u1ecb tr\u01b0\u1eddng nhanh h\u01a1n, gi\u1ea3m chi ph\u00ed ph\u00e1t tri\u1ec3n d\u01b0\u1ee3c ph\u1ea9m v\u00e0 \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3 li\u1ec1u l\u01b0\u1ee3ng t\u1ed1i \u01b0u, t\u1ea5t c\u1ea3 \u0111\u1ec1u mang l\u1ea1i \u0111\u1ed9 tin c\u1eady v\u00e0 cam k\u1ebft l\u00e2u d\u00e0i. C\u00e1c thi\u1ebft b\u1ecb v\u00e0 r\u00f4-to \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf d\u00e0nh cho ng\u01b0\u1eddi ti\u00eau d\u00f9ng l\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u mu\u1ed1n c\u00f3 t\u1ed1c \u0111\u1ed9 nhanh h\u01a1n, h\u1ec7 th\u1ed1ng ch\u00e2n kh\u00f4ng v\u00e0 nhi\u1ec7t \u0111\u1ed9 \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t t\u1ed1t h\u01a1n, c\u00f4ng su\u1ea5t l\u1edbn h\u01a1n v\u00e0 t\u0103ng t\u00ednh d\u1ec5 s\u1eed d\u1ee5ng \u0111\u1ec3 ph\u00e2n t\u00e1ch nhanh h\u01a1n, \u0111\u00e1ng tin c\u1eady h\u01a1n, th\u00f4ng l\u01b0\u1ee3ng cao h\u01a1n v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng l\u1eb7p l\u1ea1i.<\/p>\n
<\/span>S\u1ef1 tu\u00e2n th\u1ee7<\/strong><\/span><\/h2>\nKh\u1ea3 n\u0103ng truy xu\u1ea5t ngu\u1ed3n g\u1ed1c v\u00e0 h\u1ed3 s\u01a1 v\u1eadn h\u00e0nh \u0111i\u1ec7n t\u1eed c\u1ee7a ph\u1ea7n m\u1ec1m Avanti JXN v\u00e0 Optima XPN h\u1ed7 tr\u1ee3 c\u00e1c m\u00f4i tr\u01b0\u1eddng tu\u00e2n th\u1ee7 21 CFR Ph\u1ea7n 11 v\u00e0 GLP\/GMP. Ph\u1ea7n m\u1ec1m c\u00e0i s\u1eb5n theo d\u00f5i m\u1ed9t danh s\u00e1ch d\u00e0i c\u00e1c th\u00f4ng s\u1ed1 ch\u1ea1y, l\u1ecbch s\u1eed s\u1eed d\u1ee5ng, chu k\u1ef3 r\u00f4-to, v.v. Vui l\u00f2ng xem ghi ch\u00fa \u1ee9ng d\u1ee5ng CENT-512APP09.14-A \u0111\u1ec3 c\u00f3 c\u00e1i nh\u00ecn chi ti\u1ebft h\u01a1n v\u1ec1 c\u00e1ch thi\u1ebft b\u1ecb ly t\u00e2m Avanti JXN<\/a>\/Optima XPN<\/a> h\u1ed7 tr\u1ee3 tu\u00e2n th\u1ee7 21 CFR Ph\u1ea7n 11.<\/p>\n
<\/span>Linh ho\u1ea1t<\/strong><\/span><\/h2>\nL\u00e0 c\u00f4ng ty h\u00e0ng \u0111\u1ea7u th\u1ebf gi\u1edbi v\u1ec1 thi\u1ebft b\u1ecb ly t\u00e2m<\/a>, Beckman Coulter cung c\u1ea5p c\u00e1c gi\u1ea3i ph\u00e1p ly t\u00e2m gi\u00fap n\u00e2ng cao n\u0103ng su\u1ea5t, hi\u1ec7u qu\u1ea3 v\u00e0 s\u1ef1 tu\u00e2n th\u1ee7 c\u1ee7a c\u00e1c c\u01a1 s\u1edf s\u1ea3n xu\u1ea5t v\u1eafc-xin tr\u00ean to\u00e0n th\u1ebf gi\u1edbi. C\u00e1c gi\u1ea3i ph\u00e1p ly t\u00e2m c\u1ee7a Beckman Coulter \u0111\u00e1p \u1ee9ng c\u00e1c nhu c\u1ea7u c\u1ee5 th\u1ec3 c\u1ee7a d\u00e2y chuy\u1ec1n s\u1ea3n xu\u1ea5t trong su\u1ed1t qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t v\u1eafc-xin, t\u1eeb nghi\u00ean c\u1ee9u v\u00e0 ph\u00e1t tri\u1ec3n \u0111\u1ebfn s\u1ea3n xu\u1ea5t v\u00e0 x\u00e1c nh\u1eadn. D\u00f2ng s\u1ea3n ph\u1ea9m c\u1ee7a Beckman cung c\u1ea5p m\u1ed9t lo\u1ea1t h\u1ec7 th\u1ed1ng thi\u1ebft b\u1ecb ly t\u00e2m<\/a> v\u00e0 r\u00f4-to \u0111\u01b0\u1ee3c t\u1ed1i \u01b0u h\u00f3a cho ph\u00e9p c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u l\u1ef1a ch\u1ecdn lo\u1ea1i ph\u00f9 h\u1ee3p nh\u1ea5t cho nhu c\u1ea7u li\u00ean quan \u0111\u1ebfn v\u1eafc-xin c\u1ee7a h\u1ecd. M\u1ed9t th\u01b0 vi\u1ec7n t\u00edch h\u1ee3p c\u00e1c d\u1ee5ng c\u1ee5 ly t\u00e2m, r\u00f4-to, \u1ed1ng v\u00e0 ph\u1ee5 ki\u1ec7n cho ph\u00e9p m\u1ee9c \u0111\u1ed9 t\u00f9y ch\u1ec9nh v\u00e0 t\u00ednh linh ho\u1ea1t cao khi s\u1eed d\u1ee5ng c\u00e1c h\u1ec7 th\u1ed1ng Beckman Coulter, \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3, n\u0103ng su\u1ea5t v\u00e0 an to\u00e0n \u1edf m\u1ed7i b\u01b0\u1edbc trong quy tr\u00ecnh.<\/p>\n
<\/span>D\u1ec5 s\u1eed d\u1ee5ng<\/strong><\/span><\/h2>\n
$\"Quy$ <\/p>\n
Ph\u1ea7n m\u1ec1m thi\u1ebft b\u1ecb tr\u1ef1c quan, th\u00e2n thi\u1ec7n v\u1edbi ng\u01b0\u1eddi d\u00f9ng c\u1ee7a Beckman Coulter gi\u00fap d\u1ec5 d\u00e0ng l\u1eadp tr\u00ecnh c\u00e1c ho\u1ea1t \u0111\u1ed9ng c\u1ee7a thi\u1ebft b\u1ecb ly t\u00e2m<\/a> t\u1eeb trong ph\u00f2ng th\u00ed nghi\u1ec7m ho\u1eb7c th\u1eadm ch\u00ed t\u1eeb xa. Ph\u1ea7n m\u1ec1m Optima XPN\/Avanti JXN cung c\u1ea5p m\u00e0n h\u00ecnh k\u1ef9 thu\u1eadt s\u1ed1 l\u1edbn, m\u1ed9t b\u1ed9 t\u00f9y ch\u1ecdn tr\u1ee3 gi\u00fap to\u00e0n di\u1ec7n, quy tr\u00ecnh c\u00f4ng vi\u1ec7c do ng\u01b0\u1eddi d\u00f9ng l\u1eadp tr\u00ecnh v\u00e0 k\u1ebft qu\u1ea3 c\u00f3 th\u1ec3 in, t\u1ea5t c\u1ea3 \u0111\u1ec1u \u1edf \u0111\u1ecbnh d\u1ea1ng m\u00e0n h\u00ecnh c\u1ea3m \u1ee9ng. H\u1ec7 th\u1ed1ng ph\u1ea7n m\u1ec1m cho c\u1ea3 Optima XPN v\u00e0 Avanti JXN \u0111\u1ec1u nh\u1ea5t qu\u00e1n v\u1edbi nhau, gi\u00fap kh\u00e1ch h\u00e0ng d\u1ec5 d\u00e0ng chuy\u1ec3n \u0111\u1ed5i gi\u1eefa c\u00e1c c\u00f4ng c\u1ee5. H\u01a1n n\u1eefa, thi\u1ebft k\u1ebf h\u1ec7 th\u1ed1ng c\u00f4ng th\u00e1i h\u1ecdc c\u1ee7a ch\u00fang t\u00f4i n\u00e2ng cao s\u1ef1 an to\u00e0n, tho\u1ea3i m\u00e1i v\u00e0 n\u0103ng su\u1ea5t c\u1ee7a ng\u01b0\u1eddi v\u1eadn h\u00e0nh, gi\u00fap c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u lu\u00f4n vui v\u1ebb v\u00e0 kh\u1ecfe m\u1ea1nh.<\/p>\n
<\/span>Ph\u00f2ng s\u1ea1ch ph\u00f9 h\u1ee3p<\/strong><\/span><\/h2>\nH\u1ec7 th\u1ed1ng thi\u1ebft b\u1ecb ly t\u00e2m<\/a> BioSafe<\/strong> c\u1ee7a Beckman Coulter \u0111\u01b0\u1ee3c trang b\u1ecb h\u1ec7 th\u1ed1ng l\u1ecdc kh\u1eed tr\u00f9ng c\u1ea5p d\u01b0\u1ee3c ph\u1ea9m gi\u00fap gi\u1ea3m b\u1edbt lo ng\u1ea1i v\u1ec1 c\u00e1c h\u1ea1t kh\u00f4ng mong mu\u1ed1n tho\u00e1t v\u00e0o m\u00f4i tr\u01b0\u1eddng s\u1ea3n xu\u1ea5t v\u1eafc xin. B\u1ed9 l\u1ecdc kh\u1eed tr\u00f9ng d\u01b0\u1ee3c ph\u1ea9m \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t trong m\u00f4i tr\u01b0\u1eddng \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t v\u00e0 tr\u1ea3i qua qu\u00e1 tr\u00ecnh ki\u1ec3m tra t\u00ednh to\u00e0n v\u1eb9n. C\u00e1c th\u00e0nh ph\u1ea7n b\u1ed9 l\u1ecdc \u0111\u00e3 \u0111\u00e1p \u1ee9ng c\u00e1c th\u00f4ng s\u1ed1 k\u1ef9 thu\u1eadt cho c\u00e1c th\u1eed nghi\u1ec7m sinh h\u1ecdc \u0111\u01b0\u1ee3c li\u1ec7t k\u00ea trong b\u1ea3n s\u1eeda \u0111\u1ed5i hi\u1ec7n t\u1ea1i c\u1ee7a D\u01b0\u1ee3c \u0111i\u1ec3n Hoa K\u1ef3 (USP) \u0111\u1ed1i v\u1edbi nh\u1ef1a Lo\u1ea1i VI-121\u02daC v\u00e0 kh\u1ea3 n\u0103ng l\u01b0u gi\u1eef vi khu\u1ea9n tu\u00e2n th\u1ee7 c\u00e1c y\u00eau c\u1ea7u hi\u1ec7n h\u00e0nh c\u1ee7a H\u01b0\u1edbng d\u1eabn FDA S\u1ea3n ph\u1ea9m thu\u1ed1c v\u00f4 tr\u00f9ng do Aseptic s\u1ea3n xu\u1ea5t Ch\u1ebf bi\u1ebfn\u2014Th\u1ef1c h\u00e0nh s\u1ea3n xu\u1ea5t t\u1ed1t. H\u01a1n n\u1eefa, h\u1ec7 th\u1ed1ng l\u1ecdc tr\u1ea3i qua c\u00e1c b\u00e0i ki\u1ec3m tra v\u1ec1 \u0111\u1ed9 s\u1ea1ch theo Title 21 c\u1ee7a B\u1ed9 lu\u1eadt Quy \u0111\u1ecbnh Li\u00ean bang Hoa K\u1ef3 (CFR) ph\u1ea7n 211.72 v\u00e0 210.<\/p>\n
<\/span>D\u1ecbch v\u1ee5 t\u1ed1t<\/strong><\/span><\/h2>\n
Beckman Coulter \u0111\u01b0\u1ee3c c\u00f4ng nh\u1eadn r\u1ed9ng r\u00e3i khi lu\u00f4n mang nh\u1eefng gi\u1ea3i ph\u00e1p, ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 d\u1ecbch v\u1ee5 t\u1ed1t nh\u1ea5t \u0111\u1ebfn kh\u00e1ch h\u00e0ng v\u00e0 l\u00e0 s\u1ef1 l\u1ef1a ch\u1ecdn c\u1ee7a c\u00e1c c\u01a1 s\u1edf sinh h\u1ecdc tr\u00ean kh\u1eafp th\u1ebf gi\u1edbi \u0111\u1ec3 gi\u1ea3i quy\u1ebft nh\u1eefng nh\u1eefng th\u00e1ch th\u1ee9c v\u1ec1 gi\u1ea3i ph\u00e1p ly t\u00e2m. C\u00f4ng ngh\u1ec7 ly t\u00e2m \u0111\u1ec3 ph\u00e1t tri\u1ec3n v\u00e0 s\u1ea3n xu\u1ea5t v\u1eafc-xin \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u1ec3 \u0111\u00e1p \u1ee9ng c\u00e1c ti\u00eau chu\u1ea9n ch\u00ednh x\u00e1c c\u1ea7n c\u00f3 c\u1ee7a m\u00f4i tr\u01b0\u1eddng sinh h\u1ecdc. C\u00f4ng ngh\u1ec7 n\u00e0y \u0111\u01b0\u1ee3c h\u1ed7 tr\u1ee3 b\u1edfi T\u1ed5 ch\u1ee9c d\u1ecbch v\u1ee5 t\u1ea1i hi\u1ec7n tr\u01b0\u1eddng \u0111\u01b0\u1ee3c ch\u1ee9ng nh\u1eadn ISO 9001 c\u1ee7a Beckman Coulter. Bao g\u1ed3m c\u00e1c k\u1ef9 s\u01b0 \u0111\u01b0\u1ee3c \u0111\u00e0o t\u1ea1o v\u00e0 ch\u1ee9ng nh\u1eadn t\u1ea1i nh\u00e0 m\u00e1y, ho\u1ea1t \u0111\u1ed9ng d\u1ecbch v\u1ee5 c\u00f3 danh ti\u1ebfng trong ng\u00e0nh. Ngo\u00e0i ra, Beckman Coulter c\u00f2n cung c\u1ea5p Ch\u1ee9ng ch\u1ec9 l\u1eafp \u0111\u1eb7t v\u00e0 Ch\u1ee9ng ch\u1ec9 v\u1eadn h\u00e0nh (IQ\/OQ) v\u00e0 c\u00e1c nh\u00e2n vi\u00ean d\u1ecbch v\u1ee5 kh\u00e1ch h\u00e0ng c\u00f3 chuy\u00ean m\u00f4n s\u1ebd x\u1eed l\u00fd c\u00e1c y\u00eau c\u1ea7u c\u1ee7a b\u1ea1n k\u1ecbp th\u1eddi \u0111\u1ec3 gi\u1eef cho c\u01a1 s\u1edf c\u1ee7a b\u1ea1n ho\u1ea1t \u0111\u1ed9ng hi\u1ec7u qu\u1ea3.<\/p>\n
<\/span>C\u00e1c d\u00f2ng thi\u1ebft b\u1ecb ly t\u00e2m m\u1ea1nh m\u1ebd<\/strong><\/span><\/h2>\nBeckman Coulter s\u1ea3n xu\u1ea5t v\u00e0 h\u1ed7 tr\u1ee3 c\u00e1c d\u00f2ng thi\u1ebft b\u1ecb ly t\u00e2m<\/a> hi\u1ec7u su\u1ea5t cao; B\u1ea3ng 1 kh\u00f4ng ph\u1ea3i l\u00e0 danh s\u00e1ch \u0111\u1ea7y \u0111\u1ee7, nh\u01b0ng n\u00eau b\u1eadt 4 m\u00e1y ly t\u00e2m ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ee7a Beckman Coulter \u0111\u1ec3 ph\u00e1t tri\u1ec3n v\u1eafc-xin v\u00e0 c\u00e1c r\u00f4-to \u0111i k\u00e8m th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong s\u1ea3n xu\u1ea5t v\u1eafc-xin. Nhi\u1ec1u rotors c\u00f3 th\u1ec3 ho\u00e1n \u0111\u1ed5i cho nhau gi\u1eefa c\u00e1c d\u00f2ng m\u00e1y ly t\u00e2m’. Ngo\u00e0i ra, Beckman Coulter cung c\u1ea5p l\u1edbp l\u00f3t chai s\u1eed d\u1ee5ng m\u1ed9t l\u1ea7n c\u1ee7a HarvestLine gi\u00fap c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 qu\u00e1 tr\u00ecnh ly t\u00e2m v\u1eadt li\u1ec7u sinh h\u1ecdc. L\u1edbp l\u00f3t n\u00e0y lo\u1ea1i b\u1ecf vi\u1ec7c thu ho\u1ea1ch th\u1ee7 c\u00f4ng c\u00e1c ch\u1ea5t r\u1eafn t\u1eeb d\u1ee5ng c\u1ee5 ph\u00f2ng th\u00ed nghi\u1ec7m v\u00e0 t\u0103ng c\u01b0\u1eddng an to\u00e0n sinh h\u1ecdc cho ng\u01b0\u1eddi v\u1eadn h\u00e0nh. C\u00e1c l\u1edbp l\u00f3t c\u1ee7a HarvestLine c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c kh\u1eed tr\u00f9ng (chi\u1ebfu x\u1ea1 gamma) v\u00e0 \u0111\u00f4ng l\u1ea1nh \u0111\u1ec3 t\u1ea1o thu\u1eadn l\u1ee3i cho quy tr\u00ecnh s\u1ea3n xu\u1ea5t c\u1ee7a b\u1ea1n.<\/p>\n
\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
B\u1ea3ng 1. M\u00e1y ly t\u00e2m Beckman Coulter v\u00e0 R\u00f4to \u0111i k\u00e8m \u0111\u1ec3 s\u1ea3n xu\u1ea5t v\u1eafc xin.<\/strong><\/td>\n<\/tr>\n
T\u1ed1i \u01b0u XPN<\/td>\n V\u00f9ng Ti-15<\/td>\n T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 32.000 v\u00f2ng\/ph\u00fat<\/td>\n Ph\u00e2n l\u1eadp hi\u1ec7u qu\u1ea3 c\u00e1c h\u1ea1t v\u00e0 kh\u00e1ng nguy\u00ean d\u01b0\u1edbi t\u1ebf b\u00e0o<\/td>\n<\/tr>\n
Dung t\u00edch: 1.675 mL<\/td>\n<\/tr>\n
T\u1ed1c \u0111\u1ed9 d\u00f2ng ch\u1ea3y t\u1ed1i \u0111a: 50 mL\/ph\u00fat<\/td>\n<\/tr>\n
SW-32 Ti<\/td>\n t\u1ed1i \u0111a.\u00a0T\u1ed1c \u0111\u1ed9: 32.000 v\u00f2ng\/ph\u00fat<\/td>\n T\u1ed1c \u0111\u1ed9 ph\u00e2n t\u00e1ch h\u1ea1t<\/td>\n<\/tr>\n
Dung t\u00edch: 231 mL<\/td>\n<\/tr>\n
D\u00f2ng ch\u1ea3y li\u00ean t\u1ee5c CF-32 Ti<\/td>\n T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 32.000 v\u00f2ng\/ph\u00fat<\/td>\n Ph\u00e2n l\u1eadp th\u00f4ng l\u01b0\u1ee3ng cao c\u1ee7a vi r\u00fat v\u00e0 vi khu\u1ea9n l\u1edbn<\/td>\n<\/tr>\n
Dung t\u00edch: 430 mL<\/td>\n<\/tr>\n
L\u01b0u l\u01b0\u1ee3ng: 150 mL\/ph\u00fat<\/td>\n<\/tr>\n
Lo\u1ea1i 45 Ti G\u00f3c c\u1ed1 \u0111\u1ecbnh<\/td>\n T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 45.000 v\u00f2ng\/ph\u00fat<\/td>\n T\u1ed1c \u0111\u1ed9 ph\u00e2n t\u00e1ch h\u1ea1t<\/td>\n<\/tr>\n
Dung t\u00edch: 564 mL<\/td>\n<\/tr>\n
Avanti JXN-26<\/td>\n G\u00f3c c\u1ed1 \u0111\u1ecbnh JLA-8.1000<\/td>\n T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 5.000 v\u00f2ng\/ph\u00fat<\/td>\n X\u1eed l\u00fd kh\u1ed1i l\u01b0\u1ee3ng l\u1edbn t\u1ebf b\u00e0o, virus v\u00e0 ch\u1ea5t k\u1ebft t\u1ee7a<\/td>\n<\/tr>\n
Dung t\u00edch: 6.000 mL<\/td>\n<\/tr>\n
G\u00f3c c\u1ed1 \u0111\u1ecbnh JLA-9.1000<\/td>\n t\u1ed1i \u0111a.\u00a0T\u1ed1c \u0111\u1ed9: 9.000 v\u00f2ng\/ph\u00fat<\/td>\n X\u1eed l\u00fd kh\u1ed1i l\u01b0\u1ee3ng l\u1edbn t\u1ebf b\u00e0o, virus v\u00e0 ch\u1ea5t k\u1ebft t\u1ee7a<\/td>\n<\/tr>\n
Dung t\u00edch: 4.000 mL<\/td>\n<\/tr>\n
D\u1ea3i m\u00e0u \u0111\u1ecbnh h\u01b0\u1edbng l\u1ea1i JCF-Z<\/td>\n T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 20.000 v\u00f2ng\/ph\u00fat<\/td>\n X\u1eed l\u00fd vi r\u00fat, vi khu\u1ea9n v\u00e0\/ho\u1eb7c to\u00e0n b\u1ed9 t\u1ebf b\u00e0o nh\u1ecf ho\u1eb7c l\u1edbn<\/td>\n<\/tr>\n
Dung t\u00edch: 1.750 mL<\/td>\n<\/tr>\n
L\u00f5i d\u1ea1ng vi\u00ean ti\u00eau chu\u1ea9n\u00a0d\u00f2ng ch\u1ea3y li\u00ean t\u1ee5c JCF-Z<\/td>\n T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 20.000 v\u00f2ng\/ph\u00fat<\/td>\n Ph\u00e2n l\u1eadp v\u00e0 t\u1eadp trung vi-r\u00fat v\u00e0 vi khu\u1ea9n th\u00f4ng l\u01b0\u1ee3ng cao<\/td>\n<\/tr>\n
Dung t\u00edch: 1.900 mL<\/td>\n<\/tr>\n
Avanti J-HC<\/td>\n Rotor v\u0103ng JS-5.0<\/td>\n T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 5.000 v\u00f2ng\/ph\u00fat<\/td>\n Thu ho\u1ea1ch t\u1ebf b\u00e0o v\u1edbi th\u00f4ng l\u01b0\u1ee3ng r\u1ea5t cao<\/td>\n<\/tr>\n
Dung t\u00edch: 9.000 mL<\/td>\n<\/tr>\n
J6-MI<\/td>\n Rotor v\u0103ng JS-4.2<\/td>\n T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 4.200 v\u00f2ng\/ph\u00fat<\/td>\n T\u1ea1o vi\u00ean nhanh ch\u00f3ng v\u1edbi s\u1ed1 l\u01b0\u1ee3ng l\u1edbn t\u1ebf b\u00e0o, m\u1ea3nh v\u1ee5n t\u1ebf b\u00e0o v\u00e0 ch\u1ea5t k\u1ebft t\u1ee7a<\/td>\n<\/tr>\n
Dung t\u00edch: 6.000 mL<\/td>\n<\/tr>\n
M\u00e1y r\u1eeda gi\u1ea3i JE-5.0<\/td>\n T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 5.000 v\u00f2ng\/ph\u00fat<\/td>\n C\u00f4ng ngh\u1ec7 m\u1ea1nh m\u1ebd thu ho\u1ea1ch m\u1ed9t l\u01b0\u1ee3ng l\u1edbn t\u1ebf b\u00e0o kh\u1ea3 thi<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
<\/span>Quy tr\u00ecnh ph\u00e1t tri\u1ec3n v\u1eafc-xin v\u00e0 Beckman Coulter<\/strong><\/span><\/h2>\n
$\"\"$
H\u00ecnh 1.<\/strong>\u00a0Quy tr\u00ecnh \u0111i\u1ec3n h\u00ecnh \u0111\u1ec3 s\u1ea3n xu\u1ea5t v\u1eafc-xin c\u00fam t\u1eeb tr\u1ee9ng.<\/figcaption><\/figure>\n
C\u00f3 hai lo\u1ea1i ph\u00e1t tri\u1ec3n v\u1eafc-xin ch\u00ednh: d\u1ef1a tr\u00ean tr\u1ee9ng v\u00e0 d\u1ef1a tr\u00ean t\u1ebf b\u00e0o. H\u00ecnh 1 minh h\u1ecda quy tr\u00ecnh c\u00f4ng vi\u1ec7c \u0111i\u1ec3n h\u00ecnh cho s\u1ea3n xu\u1ea5t v\u1eafc-xin c\u00fam t\u1eeb tr\u1ee9ng 1. Quy tr\u00ecnh ng\u01b0\u1ee3c d\u00f2ng b\u1eaft \u0111\u1ea7u b\u1eb1ng vi\u1ec7c thu nh\u1eadn tr\u1ee9ng c\u00f3 ph\u00f4i t\u1eeb h\u1ec7 th\u1ed1ng an to\u00e0n sinh h\u1ecdc, sau \u0111\u00f3 ch\u00fang \u0111\u01b0\u1ee3c c\u1ea5y v\u00e0 \u1ee7 trong v\u00e0i ng\u00e0y \u0111\u1ec3 vi r\u00fat c\u00f3 th\u1ec3 nh\u00e2n l\u00ean \u0111\u1ea7y \u0111\u1ee7. Tr\u1ee9ng sau \u0111\u00f3 \u0111\u01b0\u1ee3c soi \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o kh\u00f4ng c\u00f3 v\u1ebft n\u1ee9t v\u00e0 sau \u0111\u00f3 \u0111\u01b0\u1ee3c l\u00e0m l\u1ea1nh qua \u0111\u00eam. Ng\u00e0y h\u00f4m sau, ch\u1ea5t l\u1ecfng allantoic \u0111\u01b0\u1ee3c thu ho\u1ea1ch v\u00e0 l\u00e0m trong b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p ly t\u00e2m th\u00edch h\u1ee3p, t\u00f9y thu\u1ed9c v\u00e0o kh\u1ed1i l\u01b0\u1ee3ng c\u1ea7n thi\u1ebft \u0111\u1ec3 s\u1ea3n xu\u1ea5t. Avanti JXN-26 l\u00e0 s\u1ef1 b\u1ed5 sung ho\u00e0n h\u1ea3o cho quy tr\u00ecnh l\u00e0m vi\u1ec7c c\u1ee7a b\u1ea1n \u1edf b\u01b0\u1edbc n\u00e0y, cung c\u1ea5p \u00e2m l\u01b0\u1ee3ng l\u1edbn v\u00e0 t\u1ed1c \u0111\u1ed9 c\u1ea7n thi\u1ebft.<\/p>\n
Vi-r\u00fat sau \u0111\u00f3 b\u1ecb v\u00f4 hi\u1ec7u h\u00f3a b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p h\u00f3a h\u1ecdc, \u0111\u01b0\u1ee3c l\u1ecdc v\u00e0 c\u00f4 \u0111\u1eb7c. Qu\u00e1 tr\u00ecnh ly t\u00e2m theo v\u00f9ng hi\u1ec7n \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n \u0111\u1ec3 t\u00e1ch vi-r\u00fat kh\u1ecfi c\u00e1c h\u1ea1t g\u00e2y \u00f4 nhi\u1ec5m kh\u00e1c theo k\u00edch th\u01b0\u1edbc v\u00e0 h\u00ecnh d\u1ea1ng trong dung d\u1ecbch sucrose. \u1ede \u0111\u00e2y, Optima XPN c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng, c\u00f3 kh\u1ea3 n\u0103ng t\u0103ng t\u1ed1c \u0111\u1ee7 nhanh \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o ph\u00e2n t\u00e1ch th\u00edch h\u1ee3p. Vi-r\u00fat \u0111\u01b0\u1ee3c ph\u1ee5c h\u1ed3i v\u00e0 ph\u00e2n t\u00e1ch b\u1eb1ng ch\u1ea5t t\u1ea9y r\u1eeda \u0111\u1ec3 h\u00f2a tan m\u00e0ng vi-r\u00fat v\u00e0 \u0111\u01b0\u1ee3c l\u00e0m s\u1ea1ch l\u1ea1i b\u1eb1ng c\u00e1ch ly t\u00e2m \u0111\u1ec3 lo\u1ea1i b\u1ecf c\u00e1c ch\u1ea5t g\u00e2y \u00f4 nhi\u1ec5m l\u1edbn. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u n\u00ean t\u1eadn d\u1ee5ng l\u1ee3i th\u1ebf c\u1ee7a Optima XPN trong b\u01b0\u1edbc n\u00e0y. C\u00e1c ti\u1ec3u \u0111\u01a1n v\u1ecb hemagglutinin v\u00e0 protein neuraminidase \u0111\u01b0\u1ee3c ph\u00e2n l\u1eadp, b\u1ea5t ho\u1ea1t b\u1edfi v\u00f2ng formalin th\u1ee9 hai, si\u00eau tinh khi\u1ebft v\u00e0 c\u00f4 \u0111\u1eb7c b\u1eb1ng c\u00e1ch l\u1ecdc.<\/p>\n
H\u1ea7u h\u1ebft c\u00e1c quy tr\u00ecnh ph\u00e1t tri\u1ec3n v\u1eafc-xin d\u1ef1a tr\u00ean tr\u1ee9ng \u0111\u1ec1u y\u00eau c\u1ea7u t\u1eeb 3 \u0111\u1ebfn 5 b\u01b0\u1edbc ly t\u00e2m \u1edf c\u00e1c t\u1ed1c \u0111\u1ed9 kh\u00e1c nhau v\u00e0 v\u1edbi c\u00e1c th\u1ec3 t\u00edch kh\u00e1c nhau t\u00f9y thu\u1ed9c v\u00e0o nhu c\u1ea7u s\u1ea3n xu\u1ea5t. Quy tr\u00ecnh n\u00e0y k\u00e9o d\u00e0i kho\u1ea3ng 7 ng\u00e0y v\u1edbi vi\u1ec7c x\u00e1c nh\u1eadn th\u00eam, l\u1eadp c\u00f4ng th\u1ee9c, ki\u1ec3m so\u00e1t ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 xu\u1ea5t x\u01b0\u1edfng theo l\u00f4 sau quy tr\u00ecnh l\u1ecdc.<\/p>\n
Thi\u1ebft b\u1ecb ly t\u00e2m<\/a> Beckman Coulter t\u01b0\u01a1ng th\u00edch v\u1edbi c\u1ea3 ph\u00f2ng th\u00ed nghi\u1ec7m ph\u00e1t tri\u1ec3n v\u1eafc-xin d\u1ef1a tr\u00ean t\u1ebf b\u00e0o v\u00e0 tr\u1ee9ng. Nhi\u1ec1u l\u1ee3i th\u1ebf ti\u1ec1m n\u0103ng t\u1ed3n t\u1ea1i v\u1edbi s\u1ef1 ph\u00e1t tri\u1ec3n v\u1eafc-xin d\u1ef1a tr\u00ean t\u1ebf b\u00e0o bao g\u1ed3m vi\u1ec7c kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o tr\u1ee9ng \u0111\u1ec3 s\u1ea3n xu\u1ea5t to\u00e0n c\u1ea7u. Ngo\u00e0i ra, quy tr\u00ecnh n\u00e0y c\u00f3 kh\u1ea3 n\u0103ng t\u00e1i s\u1ea3n xu\u1ea5t cao h\u01a1n, \u0111\u01b0\u1ee3c ti\u00eau chu\u1ea9n h\u00f3a v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng nhanh h\u01a1n. Quy tr\u00ecnh ti\u1ebfp theo c\u1ee7a qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n v\u1eafc-xin d\u1ef1a tr\u00ean t\u1ebf b\u00e0o t\u01b0\u01a1ng t\u1ef1 nh\u01b0 s\u1ea3n xu\u1ea5t d\u1ef1a tr\u00ean tr\u1ee9ng, y\u00eau c\u1ea7u c\u00e1c v\u00f2ng ly t\u00e2m, b\u1ea5t ho\u1ea1t v\u00e0 l\u1ecdc. Quy tr\u00ecnh b\u1eaft \u0111\u1ea7u b\u1eb1ng c\u00e1ch nu\u00f4i c\u1ea5y c\u00e1c t\u1ebf b\u00e0o \u0111\u01b0\u1ee3c \u0111\u00f4ng l\u1ea1nh, b\u1ea3o qu\u1ea3n trong t\u1ee7 \u1ea5m \u1edf 37\u02daC v\u1edbi kh\u1ed1i l\u01b0\u1ee3ng nh\u1ecf. Qu\u00e1 tr\u00ecnh nu\u00f4i c\u1ea5y \u0111\u01b0\u1ee3c m\u1edf r\u1ed9ng quy m\u00f4 v\u00e0 sau khi \u0111\u1ea1t \u0111\u01b0\u1ee3c m\u1eadt \u0111\u1ed9 t\u1ebf b\u00e0o c\u1ee5 th\u1ec3, vi r\u00fat h\u1ea1t gi\u1ed1ng \u0111\u01b0\u1ee3c th\u00eam v\u00e0o l\u00f2 ph\u1ea3n \u1ee9ng sinh h\u1ecdc ch\u1ee9a t\u1ebf b\u00e0o, sao cho vi r\u00fat l\u00e2y nhi\u1ec5m v\u00e0o c\u00e1c d\u00f2ng t\u1ebf b\u00e0o v\u00e0 nh\u00e2n l\u00ean.<\/p>\n
S\u1ea3n xu\u1ea5t v\u1eafc-xin \u0111\u00f2i h\u1ecfi c\u00e1c c\u00f4ng c\u1ee5 tinh vi \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u ti\u00ean ti\u1ebfn. Beckman Coulter l\u00e0 c\u00f4ng ty h\u00e0ng \u0111\u1ea7u th\u1ebf gi\u1edbi v\u1ec1 thi\u1ebft b\u1ecb ly t\u00e2m<\/a> v\u00e0 gi\u00fap ph\u00f2ng th\u00ed nghi\u1ec7m c\u1ee7a b\u1ea1n l\u1ef1a ch\u1ecdn thi\u1ebft b\u1ecb ph\u00f9 h\u1ee3p nh\u1eb1m t\u1ea1o ra quy tr\u00ecnh l\u00e0m vi\u1ec7c hi\u1ec7u qu\u1ea3 nh\u1ea5t.<\/p>\n
Ngu\u1ed3n:* https:\/\/www.beckman.com\/resources\/reading-material\/application-notes\/enhancing-vaccine-development-production<\/a><\/em><\/p>\n
\n
Minh Khang l\u00e0 nh\u00e0 ph\u00e2n ph\u1ed1i v\u00e0 nh\u1eadp kh\u1ea9u tr\u1ef1c ti\u1ebfp c\u00e1c\u00a0thi\u1ebft b\u1ecb ly t\u00e2m<\/a>\u00a0h\u00e3ng\u00a0 Beckman Coulter<\/a>.<\/strong><\/p>\n<\/div>\n
<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"
V\u1eafc-xin t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng ng\u00e0y c\u00e0ng t\u0103ng, \u0111i\u1ec1u n\u00e0y th\u00fac \u0111\u1ea9y nhu c\u1ea7u v\u1ec1 c\u00e1c s\u1ea3n ph\u1ea9m v\u1eafc-xin ng\u00e0y c\u00e0ng cao h\u01a1n, t\u1eeb ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi cho b\u1ec7nh ung th\u01b0 v\u00e0 c\u00fam theo m\u00f9a, \u0111\u1ebfn ng\u0103n ch\u1eb7n c\u00e1c m\u1ed1i \u0111e d\u1ecda kh\u1ee7ng b\u1ed1 sinh h\u1ecdc v\u00e0 c\u00e1c b\u1ec7nh truy\u1ec1n…<\/p>\n","protected":false},"author":3,"featured_media":9081,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"rank_math_lock_modified_date":false,"footnotes":""},"categories":[40],"tags":[],"class_list":["post-9005","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"acf":[],"_links":{"self":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/9005"}],"collection":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/comments?post=9005"}],"version-history":[{"count":4,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/9005\/revisions"}],"predecessor-version":[{"id":11908,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/9005\/revisions\/11908"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/media\/9081"}],"wp:attachment":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/media?parent=9005"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/categories?post=9005"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/tags?post=9005"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

B\u1ea3ng 1. M\u00e1y ly t\u00e2m Beckman Coulter v\u00e0 R\u00f4to \u0111i k\u00e8m \u0111\u1ec3 s\u1ea3n xu\u1ea5t v\u1eafc xin.<\/strong><\/td>\n<\/tr>\n
T\u1ed1i \u01b0u XPN<\/td>\n	V\u00f9ng Ti-15<\/td>\n	T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 32.000 v\u00f2ng\/ph\u00fat<\/td>\n	Ph\u00e2n l\u1eadp hi\u1ec7u qu\u1ea3 c\u00e1c h\u1ea1t v\u00e0 kh\u00e1ng nguy\u00ean d\u01b0\u1edbi t\u1ebf b\u00e0o<\/td>\n<\/tr>\n
Dung t\u00edch: 1.675 mL<\/td>\n<\/tr>\n
T\u1ed1c \u0111\u1ed9 d\u00f2ng ch\u1ea3y t\u1ed1i \u0111a: 50 mL\/ph\u00fat<\/td>\n<\/tr>\n
SW-32 Ti<\/td>\n	t\u1ed1i \u0111a.\u00a0T\u1ed1c \u0111\u1ed9: 32.000 v\u00f2ng\/ph\u00fat<\/td>\n	T\u1ed1c \u0111\u1ed9 ph\u00e2n t\u00e1ch h\u1ea1t<\/td>\n<\/tr>\n
Dung t\u00edch: 231 mL<\/td>\n<\/tr>\n
D\u00f2ng ch\u1ea3y li\u00ean t\u1ee5c CF-32 Ti<\/td>\n	T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 32.000 v\u00f2ng\/ph\u00fat<\/td>\n	Ph\u00e2n l\u1eadp th\u00f4ng l\u01b0\u1ee3ng cao c\u1ee7a vi r\u00fat v\u00e0 vi khu\u1ea9n l\u1edbn<\/td>\n<\/tr>\n
Dung t\u00edch: 430 mL<\/td>\n<\/tr>\n
L\u01b0u l\u01b0\u1ee3ng: 150 mL\/ph\u00fat<\/td>\n<\/tr>\n
Lo\u1ea1i 45 Ti G\u00f3c c\u1ed1 \u0111\u1ecbnh<\/td>\n	T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 45.000 v\u00f2ng\/ph\u00fat<\/td>\n	T\u1ed1c \u0111\u1ed9 ph\u00e2n t\u00e1ch h\u1ea1t<\/td>\n<\/tr>\n
Dung t\u00edch: 564 mL<\/td>\n<\/tr>\n
Avanti JXN-26<\/td>\n	G\u00f3c c\u1ed1 \u0111\u1ecbnh JLA-8.1000<\/td>\n	T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 5.000 v\u00f2ng\/ph\u00fat<\/td>\n	X\u1eed l\u00fd kh\u1ed1i l\u01b0\u1ee3ng l\u1edbn t\u1ebf b\u00e0o, virus v\u00e0 ch\u1ea5t k\u1ebft t\u1ee7a<\/td>\n<\/tr>\n
Dung t\u00edch: 6.000 mL<\/td>\n<\/tr>\n
G\u00f3c c\u1ed1 \u0111\u1ecbnh JLA-9.1000<\/td>\n	t\u1ed1i \u0111a.\u00a0T\u1ed1c \u0111\u1ed9: 9.000 v\u00f2ng\/ph\u00fat<\/td>\n	X\u1eed l\u00fd kh\u1ed1i l\u01b0\u1ee3ng l\u1edbn t\u1ebf b\u00e0o, virus v\u00e0 ch\u1ea5t k\u1ebft t\u1ee7a<\/td>\n<\/tr>\n
Dung t\u00edch: 4.000 mL<\/td>\n<\/tr>\n
D\u1ea3i m\u00e0u \u0111\u1ecbnh h\u01b0\u1edbng l\u1ea1i JCF-Z<\/td>\n	T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 20.000 v\u00f2ng\/ph\u00fat<\/td>\n	X\u1eed l\u00fd vi r\u00fat, vi khu\u1ea9n v\u00e0\/ho\u1eb7c to\u00e0n b\u1ed9 t\u1ebf b\u00e0o nh\u1ecf ho\u1eb7c l\u1edbn<\/td>\n<\/tr>\n
Dung t\u00edch: 1.750 mL<\/td>\n<\/tr>\n
L\u00f5i d\u1ea1ng vi\u00ean ti\u00eau chu\u1ea9n\u00a0d\u00f2ng ch\u1ea3y li\u00ean t\u1ee5c JCF-Z<\/td>\n	T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 20.000 v\u00f2ng\/ph\u00fat<\/td>\n	Ph\u00e2n l\u1eadp v\u00e0 t\u1eadp trung vi-r\u00fat v\u00e0 vi khu\u1ea9n th\u00f4ng l\u01b0\u1ee3ng cao<\/td>\n<\/tr>\n
Dung t\u00edch: 1.900 mL<\/td>\n<\/tr>\n
Avanti J-HC<\/td>\n	Rotor v\u0103ng JS-5.0<\/td>\n	T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 5.000 v\u00f2ng\/ph\u00fat<\/td>\n	Thu ho\u1ea1ch t\u1ebf b\u00e0o v\u1edbi th\u00f4ng l\u01b0\u1ee3ng r\u1ea5t cao<\/td>\n<\/tr>\n
Dung t\u00edch: 9.000 mL<\/td>\n<\/tr>\n
J6-MI<\/td>\n	Rotor v\u0103ng JS-4.2<\/td>\n	T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 4.200 v\u00f2ng\/ph\u00fat<\/td>\n	T\u1ea1o vi\u00ean nhanh ch\u00f3ng v\u1edbi s\u1ed1 l\u01b0\u1ee3ng l\u1edbn t\u1ebf b\u00e0o, m\u1ea3nh v\u1ee5n t\u1ebf b\u00e0o v\u00e0 ch\u1ea5t k\u1ebft t\u1ee7a<\/td>\n<\/tr>\n
Dung t\u00edch: 6.000 mL<\/td>\n<\/tr>\n
M\u00e1y r\u1eeda gi\u1ea3i JE-5.0<\/td>\n	T\u1ed1c \u0111\u1ed9 t\u1ed1i \u0111a: 5.000 v\u00f2ng\/ph\u00fat<\/td>\n	C\u00f4ng ngh\u1ec7 m\u1ea1nh m\u1ebd thu ho\u1ea1ch m\u1ed9t l\u01b0\u1ee3ng l\u1edbn t\u1ebf b\u00e0o kh\u1ea3 thi<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n <\/span>Quy tr\u00ecnh ph\u00e1t tri\u1ec3n v\u1eafc-xin v\u00e0 Beckman Coulter<\/strong><\/span><\/h2>\n $\"\"$ H\u00ecnh 1.<\/strong>\u00a0Quy tr\u00ecnh \u0111i\u1ec3n h\u00ecnh \u0111\u1ec3 s\u1ea3n xu\u1ea5t v\u1eafc-xin c\u00fam t\u1eeb tr\u1ee9ng.<\/figcaption><\/figure>\n C\u00f3 hai lo\u1ea1i ph\u00e1t tri\u1ec3n v\u1eafc-xin ch\u00ednh: d\u1ef1a tr\u00ean tr\u1ee9ng v\u00e0 d\u1ef1a tr\u00ean t\u1ebf b\u00e0o. H\u00ecnh 1 minh h\u1ecda quy tr\u00ecnh c\u00f4ng vi\u1ec7c \u0111i\u1ec3n h\u00ecnh cho s\u1ea3n xu\u1ea5t v\u1eafc-xin c\u00fam t\u1eeb tr\u1ee9ng 1. Quy tr\u00ecnh ng\u01b0\u1ee3c d\u00f2ng b\u1eaft \u0111\u1ea7u b\u1eb1ng vi\u1ec7c thu nh\u1eadn tr\u1ee9ng c\u00f3 ph\u00f4i t\u1eeb h\u1ec7 th\u1ed1ng an to\u00e0n sinh h\u1ecdc, sau \u0111\u00f3 ch\u00fang \u0111\u01b0\u1ee3c c\u1ea5y v\u00e0 \u1ee7 trong v\u00e0i ng\u00e0y \u0111\u1ec3 vi r\u00fat c\u00f3 th\u1ec3 nh\u00e2n l\u00ean \u0111\u1ea7y \u0111\u1ee7. Tr\u1ee9ng sau \u0111\u00f3 \u0111\u01b0\u1ee3c soi \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o kh\u00f4ng c\u00f3 v\u1ebft n\u1ee9t v\u00e0 sau \u0111\u00f3 \u0111\u01b0\u1ee3c l\u00e0m l\u1ea1nh qua \u0111\u00eam. Ng\u00e0y h\u00f4m sau, ch\u1ea5t l\u1ecfng allantoic \u0111\u01b0\u1ee3c thu ho\u1ea1ch v\u00e0 l\u00e0m trong b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p ly t\u00e2m th\u00edch h\u1ee3p, t\u00f9y thu\u1ed9c v\u00e0o kh\u1ed1i l\u01b0\u1ee3ng c\u1ea7n thi\u1ebft \u0111\u1ec3 s\u1ea3n xu\u1ea5t. Avanti JXN-26 l\u00e0 s\u1ef1 b\u1ed5 sung ho\u00e0n h\u1ea3o cho quy tr\u00ecnh l\u00e0m vi\u1ec7c c\u1ee7a b\u1ea1n \u1edf b\u01b0\u1edbc n\u00e0y, cung c\u1ea5p \u00e2m l\u01b0\u1ee3ng l\u1edbn v\u00e0 t\u1ed1c \u0111\u1ed9 c\u1ea7n thi\u1ebft.<\/p>\n Vi-r\u00fat sau \u0111\u00f3 b\u1ecb v\u00f4 hi\u1ec7u h\u00f3a b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p h\u00f3a h\u1ecdc, \u0111\u01b0\u1ee3c l\u1ecdc v\u00e0 c\u00f4 \u0111\u1eb7c. Qu\u00e1 tr\u00ecnh ly t\u00e2m theo v\u00f9ng hi\u1ec7n \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n \u0111\u1ec3 t\u00e1ch vi-r\u00fat kh\u1ecfi c\u00e1c h\u1ea1t g\u00e2y \u00f4 nhi\u1ec5m kh\u00e1c theo k\u00edch th\u01b0\u1edbc v\u00e0 h\u00ecnh d\u1ea1ng trong dung d\u1ecbch sucrose. \u1ede \u0111\u00e2y, Optima XPN c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng, c\u00f3 kh\u1ea3 n\u0103ng t\u0103ng t\u1ed1c \u0111\u1ee7 nhanh \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o ph\u00e2n t\u00e1ch th\u00edch h\u1ee3p. Vi-r\u00fat \u0111\u01b0\u1ee3c ph\u1ee5c h\u1ed3i v\u00e0 ph\u00e2n t\u00e1ch b\u1eb1ng ch\u1ea5t t\u1ea9y r\u1eeda \u0111\u1ec3 h\u00f2a tan m\u00e0ng vi-r\u00fat v\u00e0 \u0111\u01b0\u1ee3c l\u00e0m s\u1ea1ch l\u1ea1i b\u1eb1ng c\u00e1ch ly t\u00e2m \u0111\u1ec3 lo\u1ea1i b\u1ecf c\u00e1c ch\u1ea5t g\u00e2y \u00f4 nhi\u1ec5m l\u1edbn. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u n\u00ean t\u1eadn d\u1ee5ng l\u1ee3i th\u1ebf c\u1ee7a Optima XPN trong b\u01b0\u1edbc n\u00e0y. C\u00e1c ti\u1ec3u \u0111\u01a1n v\u1ecb hemagglutinin v\u00e0 protein neuraminidase \u0111\u01b0\u1ee3c ph\u00e2n l\u1eadp, b\u1ea5t ho\u1ea1t b\u1edfi v\u00f2ng formalin th\u1ee9 hai, si\u00eau tinh khi\u1ebft v\u00e0 c\u00f4 \u0111\u1eb7c b\u1eb1ng c\u00e1ch l\u1ecdc.<\/p>\n H\u1ea7u h\u1ebft c\u00e1c quy tr\u00ecnh ph\u00e1t tri\u1ec3n v\u1eafc-xin d\u1ef1a tr\u00ean tr\u1ee9ng \u0111\u1ec1u y\u00eau c\u1ea7u t\u1eeb 3 \u0111\u1ebfn 5 b\u01b0\u1edbc ly t\u00e2m \u1edf c\u00e1c t\u1ed1c \u0111\u1ed9 kh\u00e1c nhau v\u00e0 v\u1edbi c\u00e1c th\u1ec3 t\u00edch kh\u00e1c nhau t\u00f9y thu\u1ed9c v\u00e0o nhu c\u1ea7u s\u1ea3n xu\u1ea5t. Quy tr\u00ecnh n\u00e0y k\u00e9o d\u00e0i kho\u1ea3ng 7 ng\u00e0y v\u1edbi vi\u1ec7c x\u00e1c nh\u1eadn th\u00eam, l\u1eadp c\u00f4ng th\u1ee9c, ki\u1ec3m so\u00e1t ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 xu\u1ea5t x\u01b0\u1edfng theo l\u00f4 sau quy tr\u00ecnh l\u1ecdc.<\/p>\n Thi\u1ebft b\u1ecb ly t\u00e2m<\/a> Beckman Coulter t\u01b0\u01a1ng th\u00edch v\u1edbi c\u1ea3 ph\u00f2ng th\u00ed nghi\u1ec7m ph\u00e1t tri\u1ec3n v\u1eafc-xin d\u1ef1a tr\u00ean t\u1ebf b\u00e0o v\u00e0 tr\u1ee9ng. Nhi\u1ec1u l\u1ee3i th\u1ebf ti\u1ec1m n\u0103ng t\u1ed3n t\u1ea1i v\u1edbi s\u1ef1 ph\u00e1t tri\u1ec3n v\u1eafc-xin d\u1ef1a tr\u00ean t\u1ebf b\u00e0o bao g\u1ed3m vi\u1ec7c kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o tr\u1ee9ng \u0111\u1ec3 s\u1ea3n xu\u1ea5t to\u00e0n c\u1ea7u. Ngo\u00e0i ra, quy tr\u00ecnh n\u00e0y c\u00f3 kh\u1ea3 n\u0103ng t\u00e1i s\u1ea3n xu\u1ea5t cao h\u01a1n, \u0111\u01b0\u1ee3c ti\u00eau chu\u1ea9n h\u00f3a v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng nhanh h\u01a1n. Quy tr\u00ecnh ti\u1ebfp theo c\u1ee7a qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n v\u1eafc-xin d\u1ef1a tr\u00ean t\u1ebf b\u00e0o t\u01b0\u01a1ng t\u1ef1 nh\u01b0 s\u1ea3n xu\u1ea5t d\u1ef1a tr\u00ean tr\u1ee9ng, y\u00eau c\u1ea7u c\u00e1c v\u00f2ng ly t\u00e2m, b\u1ea5t ho\u1ea1t v\u00e0 l\u1ecdc. Quy tr\u00ecnh b\u1eaft \u0111\u1ea7u b\u1eb1ng c\u00e1ch nu\u00f4i c\u1ea5y c\u00e1c t\u1ebf b\u00e0o \u0111\u01b0\u1ee3c \u0111\u00f4ng l\u1ea1nh, b\u1ea3o qu\u1ea3n trong t\u1ee7 \u1ea5m \u1edf 37\u02daC v\u1edbi kh\u1ed1i l\u01b0\u1ee3ng nh\u1ecf. Qu\u00e1 tr\u00ecnh nu\u00f4i c\u1ea5y \u0111\u01b0\u1ee3c m\u1edf r\u1ed9ng quy m\u00f4 v\u00e0 sau khi \u0111\u1ea1t \u0111\u01b0\u1ee3c m\u1eadt \u0111\u1ed9 t\u1ebf b\u00e0o c\u1ee5 th\u1ec3, vi r\u00fat h\u1ea1t gi\u1ed1ng \u0111\u01b0\u1ee3c th\u00eam v\u00e0o l\u00f2 ph\u1ea3n \u1ee9ng sinh h\u1ecdc ch\u1ee9a t\u1ebf b\u00e0o, sao cho vi r\u00fat l\u00e2y nhi\u1ec5m v\u00e0o c\u00e1c d\u00f2ng t\u1ebf b\u00e0o v\u00e0 nh\u00e2n l\u00ean.<\/p>\n S\u1ea3n xu\u1ea5t v\u1eafc-xin \u0111\u00f2i h\u1ecfi c\u00e1c c\u00f4ng c\u1ee5 tinh vi \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u ti\u00ean ti\u1ebfn. Beckman Coulter l\u00e0 c\u00f4ng ty h\u00e0ng \u0111\u1ea7u th\u1ebf gi\u1edbi v\u1ec1 thi\u1ebft b\u1ecb ly t\u00e2m<\/a> v\u00e0 gi\u00fap ph\u00f2ng th\u00ed nghi\u1ec7m c\u1ee7a b\u1ea1n l\u1ef1a ch\u1ecdn thi\u1ebft b\u1ecb ph\u00f9 h\u1ee3p nh\u1eb1m t\u1ea1o ra quy tr\u00ecnh l\u00e0m vi\u1ec7c hi\u1ec7u qu\u1ea3 nh\u1ea5t.<\/p>\n Ngu\u1ed3n: https:\/\/www.beckman.com\/resources\/reading-material\/application-notes\/enhancing-vaccine-development-production<\/a><\/em><\/p>\n \n Minh Khang l\u00e0 nh\u00e0 ph\u00e2n ph\u1ed1i v\u00e0 nh\u1eadp kh\u1ea9u tr\u1ef1c ti\u1ebfp c\u00e1c\u00a0thi\u1ebft b\u1ecb ly t\u00e2m<\/a>\u00a0h\u00e3ng\u00a0 Beckman Coulter<\/a>.<\/strong><\/p>\n<\/div>\n <\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":" V\u1eafc-xin t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng ng\u00e0y c\u00e0ng t\u0103ng, \u0111i\u1ec1u n\u00e0y th\u00fac \u0111\u1ea9y nhu c\u1ea7u v\u1ec1 c\u00e1c s\u1ea3n ph\u1ea9m v\u1eafc-xin ng\u00e0y c\u00e0ng cao h\u01a1n, t\u1eeb ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi cho b\u1ec7nh ung th\u01b0 v\u00e0 c\u00fam theo m\u00f9a, \u0111\u1ebfn ng\u0103n ch\u1eb7n c\u00e1c m\u1ed1i \u0111e d\u1ecda kh\u1ee7ng b\u1ed1 sinh h\u1ecdc v\u00e0 c\u00e1c b\u1ec7nh truy\u1ec1n…<\/p>\n","protected":false},"author":3,"featured_media":9081,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"rank_math_lock_modified_date":false,"footnotes":""},"categories":[40],"tags":[],"class_list":["post-9005","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"acf":[],"_links":{"self":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/9005"}],"collection":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/comments?post=9005"}],"version-history":[{"count":4,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/9005\/revisions"}],"predecessor-version":[{"id":11908,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/posts\/9005\/revisions\/11908"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/media\/9081"}],"wp:attachment":[{"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/media?parent=9005"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/categories?post=9005"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gd-1.com\/wp-json\/wp\/v2\/tags?post=9005"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}